Search or ask a question

Can bilirubin levels be normal with cirrhosis?

Viral hepatitis

Primary biliary cirrhosis

Answers from top 3 papers

PDF

Open Access

More filters

Papers (3)	Insight
Open access•Journal Article•DOI Bilirubin alone as a biomarker for short-term mortality in acute-on-chronic liver failure: an important prognostic indicator. Jorge A. López-Velázquez, Norberto C. Chávez-Tapia, Guadalupe Ponciano-Rodríguez, Vicente Sánchez-Valle, Stephen H. Caldwell, Misael Uribe, Nahum Méndez-Sánchez - Show less +6 more 01 Jan 2014-Annals of Hepatology 56 Citations	High levels of bilirubin are able to predict short-term mortality in these patients.
Journal Article•DOI Clinical value of serum bilirubin subfractionation by high-performance liquid chromatography and conventional methods in patients with primary biliary cirrhosis Peter L.M. Jansen, Wilbert H.M. Peters, A. Roelof Janssens - Show less +2 more 01 Jan 1986-Journal of Hepatology 15 Citations	The presence of bilirubin conjugates and 'bilirubin-albumin' in serum suggests liver disease.
Open access•Journal Article•DOI UGT1A1*28 relationship with abnormal total bilirubin levels in chronic hepatitis C patients: Outcomes from a case-control study. Marcelo Moreira Tavares de Souza, Victor Van Vaisberg, Rodrigo Martins Abreu, Aline Siqueira Ferreira, Camila daSilvaFerreira, Paulo Dominguez Nasser, Helena Scavone Paschoale, Flair José Carrilho, Suzane Kioko Ono - Show less +8 more 01 Mar 2017-Medicine 8 Citations	Bilirubin levels are linked to the studied polymorphisms, and this is the first time that these findings are reported in a chronic liver disease sample.

My columns

Related Questions

What do rising bilirubin levels mean for HCC?5 answersRising bilirubin levels in the context of Hepatocellular Carcinoma (HCC) have significant implications. Elevated bilirubin levels have been associated with a decreased positive predictive value for diagnosing HCC, while the negative predictive value increases. Additionally, in patients with specific ranges of alpha-fetoprotein (AFP) and bilirubin levels, monitoring trends in serum gamma-glutamyl transferase (GGTP) levels can aid in diagnosing small HCCs. Moreover, high bilirubin levels have been linked to a poorer prognosis in HCC patients treated with sorafenib, potentially impacting treatment efficacy. Furthermore, an increased Albumin-Bilirubin (ALBI) score, which includes bilirubin levels, has been identified as a significant risk factor for the occurrence of HCC in patients with liver cirrhosis, highlighting the predictive value of bilirubin levels in HCC development.

Is bilirubin associated with NAFLD?5 answersBilirubin levels have been found to have an inverse correlation with the incidence rate of non-alcoholic fatty liver disease (NAFLD). Serum total bilirubin (TBIL) and direct bilirubin (DBIL) levels, especially DBIL levels, have been shown to have an inverse correlation with metabolic syndrome (MetS) in healthy populations. However, a study on non-obese Chinese adults found no significant association between serum bilirubin levels and NAFLD in this population. In Italian obese children and adolescents, serum bilirubin levels were not associated with NAFLD as a whole, but were inversely associated with selected components of metabolic syndrome. Another study on a Chinese Han population found that circulating TB levels were higher in patients with moderate and severe steatosis, and weakly associated with liver fat fraction in NAFLD patients. Overall, while there is evidence of an inverse association between bilirubin levels and NAFLD in some populations, the relationship is still unclear and further research is needed.

Can GGT be normal in cirrhosis?6 answers

How high are your liver enzymes with cirrhosis?5 answers

Is Bun elevated in cirrhosis?5 answers

Why is bun high in cirrhosis?6 answers

See what other people are reading

How does pomegranate extract affect hepatic cholesterol-bile acid metabolism in individuals with non-alcoholic fatty liver disease (NAFLD)?

What is the significance of cloning the HBV surface gene in Pichia pastoris for vaccine development?

What is the significance of cloning the HBV surface gene in Pichia pastoris for vaccine development?

What are healthcare professionals perceptions of management strategies for alpha-1 antitrypsin deficiency associated liver disease?

How do hepatitis A, B, C, D, and E differ in terms of transmission, symptoms, and treatment?

Hepatitis A and E are mainly transmitted through the fecal-oral route, while hepatitis B, C, and D are transmitted through exposure to infected blood. Symptoms of hepatitis A and E typically result in acute, self-limiting liver injury, with rare severe outcomes. In contrast, hepatitis B, C, and D can lead to chronic infections, cirrhosis, and even liver cancer. Treatment for hepatitis A mainly involves supportive measures, while hepatitis B and C have highly effective antiviral therapies. Hepatitis D treatment includes inhibiting virus uptake. Vaccines are available for hepatitis A and B, with promising developments for hepatitis E. Overall, understanding the differences in transmission, symptoms, and treatment is crucial for managing these viral infections effectively.Sds bands at end of the SDS PAGE?

At the end of SDS-PAGE, protein bands may appear at unexpected molecular masses, cautioning against definitive interpretations. Studies have shown that bands with apparent molecular masses different from the theoretical values are common. To enhance band contrast in stained gels and improve automated band detection, a rapid and reversible method utilizing alcohols has been developed. SDS-PAGE has been utilized to analyze milk protein distribution, revealing distinct protein bands in goat milk whey samples with varying molecular weights. Additionally, SDS-PAGE has been employed to differentiate economically important nematode species based on distinct protein bands, aiding in species-level diagnosis. These findings collectively emphasize the importance of careful interpretation and innovative techniques in SDS-PAGE analysis for accurate protein characterization.What is the follow-up time of cirrhosis patients in China？?

The follow-up time of cirrhosis patients in China varies based on the studies. One study followed patients from June 2006 to October 2010, with a mean follow-up time of 17 months, ranging from 1.0 to 52.2 months. Another study focused on patients with cirrhosis and acute decompensation, where data was collected until the end of 365 days or until death or liver transplantation. Additionally, a study spanning from January 1, 2018, to December 31, 2020, analyzed patients diagnosed with liver cirrhosis for the first time, but the specific follow-up duration was not mentioned. Therefore, follow-up times for cirrhosis patients in China can range from months to a year, depending on the specific study and patient cohort.What is the mechanism of action of chrozophora tinctoria extract in reducing liver tissue damage?

The mechanism of action of Chrozophora tinctoria extract in reducing liver tissue damage involves its antioxidant and anti-inflammatory properties. Studies have shown that the extract significantly decreases liver enzyme levels, such as AST, ALT, and ALP, while increasing antioxidant enzyme parameters like CAT, SOD, GGT, and GST. Additionally, the extract reduces oxidative stress markers, proinflammatory cytokines, and levels of malondialdehyde and nitric oxide in the liver. Furthermore, Chrozophora tinctoria extract has been found to improve liver function, reduce lesions associated with liver damage, and protect against hepatotoxicity induced by substances like carbon tetrachloride. These combined effects demonstrate the hepatoprotective potential of Chrozophora tinctoria extract through its multifaceted antioxidant and anti-inflammatory actions.Correlation between the use of transcutaneous bilirubinometer on the forehead and chest and serum bilirubinometry in neonates with jaundice?

The correlation between transcutaneous bilirubinometer measurements on the forehead and chest compared to serum bilirubin levels in neonates with jaundice was investigated in several studies. Studies have shown that transcutaneous bilirubinometry is a reliable screening tool for hyperbilirubinemia. The effectiveness of transcutaneous bilirubin measurements on the chest and forehead in predicting hyperbilirubinemia was found to be acceptable, with slightly less accuracy on the forehead. Additionally, the accuracy of transcutaneous bilirubinometry on the sternum was highlighted, showing it to be more predictive than on the forehead, especially before phototherapy, for assessing the need for treatment in outpatient settings. These findings suggest that transcutaneous bilirubin measurements, particularly on the sternum, can serve as valuable tools in evaluating neonatal jaundice.Are liver disease patients in the UK malnourished?

Liver disease patients in the UK, particularly those with cirrhosis, are at risk of malnutrition. Malnutrition prevalence in cirrhosis patients ranges from 5% to 92%, highlighting the significance of this issue. Screening tools like the Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT) and Nutritional Risk Screening 2002 (NRS2002) are commonly used to detect malnutrition risk in these patients. Studies have shown that malnutrition risk, assessed by RFH-NPT, is independently associated with low health-related quality of life (HRQoL) in cirrhosis patients. Early identification of malnutrition risk is crucial for improving outcomes, as malnourished cirrhosis patients have higher mortality rates. Therefore, regular screening and assessment for malnutrition should be prioritized in the care of liver disease patients in the UK to enhance their overall health and well-being.What is the current hepatitis E hospitalization rate in Bangladesh?

The current hospitalization rate for hepatitis E in Bangladesh is significant. A study conducted in six tertiary hospitals from December 2014 to September 2017 found that out of 1925 hospitalized acute jaundice patients aged 14 years and above, 34% were diagnosed with acute hepatitis E. Additionally, another study revealed that acute viral hepatitis E is a leading cause of liver disease in young male adults in Bangladesh, with a high incidence of acute viral hepatitis E cases observed. These findings highlight the substantial burden of hepatitis E in Bangladesh, emphasizing the importance of effective control measures and interventions to reduce the impact of this disease on public health.