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Can copper peptides replace vitamin C? 

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The use of Cu(+)/Cu(2+)-binding peptides might be beneficial in the treatment of ROS-related diseases associated with copper.
This work shows that affinity chromatography can be used for the purification of copper-chelating peptides and probably other metals of nutritional interest such as calcium, iron, and zinc.
The overall results indicate that copper(II) can bind these peptides using the histidine residue or amino group as anchoring sites and that copper(II) binding may have a possible involvement in AD.
Therefore, organic compounds that can interfere with copper homeostasis may find therapeutic application in copper-dependent diseases.
Moreover, the use of Cys-containing peptides allowed us to design sites structurally similar to the copper-binding sites of biomolecules involved in copper trafficking and homeostasis.

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