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Can Covid antibodies pass through placenta? 

Antibody titer
Antibody
Fetus
Pregnancy
Cord blood

Answers from top 8 papers

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Papers (8)Insight
Journal Article•DOI
Placental transfer favours high avidity IgG antibodies.
M.A. Avanzini, P Pignatti, Gaetano Chirico, Antonella Gasparoni, Fehmida Jalil, L. Å. Hanson 
02 Jan 2007-Acta Paediatrica
33 Citations
Our data suggest that high avidity antibodies preferentially cross the placenta; this seems to start early during gestation and appears to be related to the nature of the antigen to which the antibodies are directed, but not to the degree of antigenic exposure.
Journal Article•DOI
Evidence for the presence of neutralizing antibodies against human papillomavirus type 6 in infants born to mothers with condyloma acuminata.
Kei Kawana, Toshiharu Yasugi, Hiroyuki Yoshikawa, Yukiko Kawana, Koji Matsumoto, Shunsuke Nakagawa, Takashi Onda, Akihiko Kikuchi, Tomoyuki Fujii, Tadahito Kanda, Yuji Taketani 
01 Jan 2003-American Journal of Perinatology
24 Citations
This is the first report to describe that neutralizing antibodies against HPV6 in mothers with CA go through the placenta and enter the circulation of their infants.
Open access•Journal Article
Transfer of antibodies directed to paternal major histocompatibility class I antigens from pregnant mice to the developing fetus.
S. C. A. Adeniyi-Jones, K. Ozato 
01 Mar 1987-Journal of Immunology
20 Citations
Our results indicate that antibodies are transferred by way of the placenta and yolk sac, and reach the fetus predominantly via the circulation.
Journal Article•DOI
Maternal immunization: Optimizing protection for the mother and infant.
Alisa Kachikis, Janet A. Englund 
05 Jul 2016-Journal of Infection
40 Citations
The ability of maternal immunoglobulin IgG antibodies to be transported readily across the healthy intact placenta depends on many different factors including gestational age in the pregnancy, nature and timing of the immunization and presence of maternal HIV or malaria infections.
Open access•Journal Article•DOI
Placental antibody transfer efficiency and maternal levels: specific for measles, coxsackievirus A16, enterovirus 71, poliomyelitis I-III and HIV-1 antibodies
Chuanxi Fu, Long Lu, Hao Wu, Jeffrey Shaman, Yimin Cao, Fang Fang, Qiongying Yang, Qing He, Zhicong Yang, Ming Wang 
09 Dec 2016-Scientific Reports
54 Citations
Maternal antibodies transported across the placenta can provide vital immunity against infectious pathogens for infants.
Journal Article•DOI
Viral antibodies in maternal and cord sera
T Gotlieb-Stematsky, I Meron, Michaela Modan, Y Sayar, S Leventon-Kriss, A Fogel, R Gurewitz, V Insler 
01 Jan 1983-Medical Microbiology and Immunology
20 Citations
These results indicate an efficient and selective transfer through the placenta of certain viral antibodies and the possible association of lower antibody production with the presence of risk indicators in the infants.
Journal Article•DOI
Diaplacental Infection of the Foetus With the Virus of German Measles Despite Immunity of the Mother: Analogous Observations in Smallpox
Béla Schick
01 Nov 1949-Acta Paediatrica
17 Citations
Even rapid (accelerated) reproduction of antibodies may come too late to prevent the passage of the virus through the placenta to the foetus.
Open access•Journal Article•DOI
Acquisition of Maternal Antibodies both from the Placenta and by Lactation Protects Mouse Offspring from Yersinia pestis Challenge
Zhizhen Qi, Haihong Zhao, Qingwen Zhang, Yujing Bi, Lingling Ren, Xuecan Zhang, Hanqing Yang, Xiaoyan Yang, Qiong Wang, Cunxiang Li, Jiyuan Zhou, Youquan Xin, Yonghai Yang, Huiying Yang, Zongmin Du, Yafang Tan, Yanping Han, Yajun Song, Lei Zhou, Pingping Zhang, Yujun Cui, Yanfeng Yan, Dongsheng Zhou, Ruifu Yang, Xiaoyi Wang 
01 Nov 2012-Clinical and Vaccine Immunology
13 Citations
These results indicated that maternal antibodies induced by the plague subunit vaccine in mother mice can be transferred to NM by both placenta and lactation.

Related Questions

How does Sars1 affect t the placenta?5 answersSARS-CoV-2 infection impacts the placenta in various ways. Studies have shown that SARS-CoV-2 infection during pregnancy can lead to alterations in placental mitochondrial features, oxidative balance, and gene expressions related to antioxidant defenses, mitochondrial dynamics, and respiratory chain subunits. Additionally, SARS-CoV-2 Alpha variant infection has been linked to placental insufficiency, intervillous fibrin deposition, ischemic necrosis of villi, and histiocytic intervillositis, indicating significant placental pathology and subsequent fetal distress. The virus colonizes ACE2-expressing maternal and fetal cells in the placenta, leading to reduced ACE2 levels and alterations in the renin-angiotensin system, potentially increasing the risk of adverse hemodynamic outcomes like preeclampsia in pregnant women. Histopathological examinations have revealed features of fetal and maternal malperfusion, such as chorangiosis and villous crowding, suggesting a potential rise in adverse perinatal outcomes like intrauterine fetal growth retardation and preterm birth.
What immune markers pass through the placenta from mother to embryo?4 answersAntibodies of the IgG class are the primary immune markers that pass through the placenta from mother to embryo, conferring passive immunity to the fetus. Additionally, maternal immune activation markers such as sCD8, sIL-2R, and β2 m have been detected in both maternal and fetal compartments, suggesting transport or diffusion from the mother to the fetus. Furthermore, the placenta has been shown to express minor histocompatibility antigens (mHAgs) and release trophoblast-derived exosomes containing immune molecules like HLA-DR, which can influence dendritic cell phenotype. These findings highlight the crucial role of the placenta in transferring immune markers and providing protection to the developing embryo.
Can pregnant women receive antibodies for Covid?8 answers
Can you pass Covid antibodies in breastmilk?4 answers
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