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Reduced glutathione was significantly decreased, suggesting glutathione depletion due to oxida-tive stress.
This is the first report on regulation of glutathione metabolism and glutathione related enzymes in response to ER stress in plants.
Modifications in the activity of the glutathione cycle may provide treatment options.
Glutathione is a critical factor in protecting organisms against toxicity and disease.
The protective effects appeared to be caused by an increase in glutathione (GSH).
These findings could be explained by an increase of glutathione synthesis brought about by the stimulation of glutathione synthetase activity.
This suggest that osmotic depletion of glutathione is not due to cellular efflux of intact glutathione.
In the present study we provide evidence that the utilization of glutathione can occur in the absence of gamma-GT.
Overall, glutathione in both forms are well tolerated.
These findings suggest that there may be at least two pools of glutathione.
There is good evidence that glutathione functions in several different ways.