Can glutathione cause skin cancer?
Answers from top 11 papers
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| Papers (11) | Insight |
|---|---|
101 Citations | In the short term, glutathione-based systems should continue to provide viable targets and a platform for the development of novel cancer drugs. |
33 Citations | An elevated tumor glutathione level at the time of diagnosis appears to confer a poor prognosis in patients with colorectal cancer. |
50 Citations | In conclusion the glutathione content was associated with progression of ovarian carcinomas but neither glutathione nor glutathione S -transferases α and π or aldehyde dehydrogenase were independent factors of resistance to cyclophosphamide/carboplatin. |
31 Citations | Continuing development and optimization of glutathione analogues will lead to more specific targeting of this system in cancer treatment, allowing an increased therapeutic response. |
12 Citations | Results of the study suggest that erythrocytes from cancer patients responded to oxidative stress by elevating glutathione levels, while a decrease in glutathione levels observed in Group B, could be due to the free radical scavenging effect of OF, sparing the glutathione. |
789 Citations | With respect to cancer, glutathione metabolism is able to play both protective and pathogenic roles. |
204 Citations | Our results indicate that determination of glutathione status and oxidative stress-related parameters in blood may help to orientate cancer therapy in humans. |
16 Citations | Under these experimental conditions, the long term administration of glutathione appears to have no observable influence on liver cancer development in this model. |
| Our study suggests that dysregulation of glutathione levels in head and neck cancer has the potential to predict metastasis, and may serve as a prognostic marker. | |
126 Citations | Available evidence is consistent with this hypothesis, although a definitive role for glutathione system genes in lung cancer prognosis needs to be elucidated. |
66 Citations | Currently, there are three randomized controlled trials that support the skin-lightening effect and good safety profile of topical and oral glutathione. |