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Can I drink coffee while taking glutathione?

Glutathione reductase

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Open access•Journal Article•DOI Glutathione and its antiaging and antimelanogenic effects. Sinee Weschawalit, Siriwan Thongthip, Phanupong Phutrakool, Pravit Asawanonda - Show less +3 more 27 Apr 2017-Clinical, Cosmetic and Investigational Dermatology 61 Citations	Overall, glutathione in both forms are well tolerated.
Journal Article•DOI Selenium-induced oxidative stress in coffee cell suspension cultures Rui A. Gomes-Junior, Priscila Lupino Gratão, Salete Aparecida Gaziola, Paulo Mazzafera, Peter J. Lea, Ricardo Antunes Azevedo - Show less +5 more 12 Jun 2007-Functional Plant Biology 99 Citations	An extra isoenzyme of glutathione reductase (GR) was induced in the presence of selenite, which confirmed our previous results obtained with Cd and Ni indicating that this GR isoenzyme may have the potential to be a marker for oxidative stress in coffee.
Journal Article•DOI Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells Thomas Efferth, Ursula Fabry, P. Glatte, R. Osieka - Show less +3 more 01 Jan 1995-Journal of Cancer Research and Clinical Oncology 37 Citations	We conclude that the effect of caffeine on glutathione depletion represents a mechanism of action by which caffeine can modulate apoptosis.
Open access•Journal Article•DOI Utilization of glutathione as an exogenous sulfur source is independent of γ-glutamyl transpeptidase in the yeast Saccharomyces cerevisiae: evidence for an alternative gluathione degradation pathway Chitranshu Kumar, Rakesh Sharma, Anand K. Bachhawat - Show less +2 more 01 Feb 2003-Fems Microbiology Letters 38 Citations	In the present study we provide evidence that the utilization of glutathione can occur in the absence of gamma-GT.
Open access•Journal Article•DOI Depletion of glutathione from brain cells in hyponatremia Edward C. Clark, Darbbie Thomas, Jane E. Baer, Richard H. Sterns - Show less +3 more 01 Feb 1996-Kidney International 25 Citations	This suggest that osmotic depletion of glutathione is not due to cellular efflux of intact glutathione.
Journal Article•DOI The systemic availability of oral glutathione. A. Witschi, S. Reddy, B. Stofer, Bernhard H. Lauterburg - Show less +3 more 01 Jan 1992-European Journal of Clinical Pharmacology 258 Citations	During the 270 min after the administration of glutathione in a dose of 0.15 mmol·kg−1 the concentrations of glutathione, cysteine, and glutamate in plasma did not increase significantly, suggesting that the systemic availability of glutathione is negligible in man. Because of hydrolysis of glutathione by intestinal and hepatic γ-glutamyltransferase, dietary glutathione is not a major determinant of circulating glutathione, and it is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of 3 g of glutathione.

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