scispace - formally typeset
Search or ask a question

Can I stop my diabetes medicines and insulin and take two gooseberry everyday? 

Answers from top 10 papers

More filters
Papers (10)Insight
Open accessJournal ArticleDOI
16 Citations
The treatment is variable regarding to the type of diabetes, but daily administration of insulin can be needed.
Lifestyle changes can be implemented and medications can be administered to improve insulin sensitivity, insulin secretion, and glucose utilization and reduce the prevalence of type 2 diabetes.
Insulin resistance and type 2 diabetes can be prevented and controlled naturopathically and herbal medicine can play a primary role in the management of dysglycemia.
Good diabetes control can be achieved in routine diabetes care with flexible intensified insulin therapy based on continuing patients' education and with a minimum of 4 SMBGs per day.
Complications from diabetes, which can be devastating, could largely be prevented by wider use of several inexpensive generic medicines, simple tests and monitoring and can be a cost saving intervention.
For diabetes, frequent insulin treatment is very expensive and may increase anti‐insulin antibody production, which may cause unwanted side effects.
In adults at risk for diabetes, LSM and medications (weight loss and insulin-sensitizing agents) successfully reduced diabetes incidence.
These findings suggest that the presence of insulin resistance in Type 1 diabetes or "double diabetes" plays a key role in determining daily insulin need.
Treatment of diabetes mellitus as a multifactorial disease using herbal medicines requires a comprehensive approach.
Under everyday conditions of primary diabetes care, dual therapy with M-Sita can be maintained for longer than M-SU.

See what other people are reading

Which specific microRNAs have been found to be dysregulated in individuals with obesity and metabolic inflexibility?
5 answers
Several microRNAs (miRNAs) have been identified as dysregulated in individuals with obesity and metabolic inflexibility. In obese individuals with metabolic syndrome, miR-331-3p, miR-452-3p, and miR-485-5p were found to be over-expressed, while miR-153-3p, miR-182-5p, and miR-433-3p were under-expressed. Additionally, miRNAs 122 and 192 were significantly correlated with markers of inflammation and metabolic disorders in pediatric obesity. Furthermore, in response to a high-carbohydrate meal, miR-15a-5p and miR-17-5p levels were altered in healthy weight individuals but remained unchanged in overweight insulin-resistant women, indicating a potential link to metabolic inflexibility. These dysregulated miRNAs play crucial roles in metabolic regulation and may serve as markers for identifying individuals predisposed to metabolic diseases associated with obesity.
Does a History of Gestational Diabetes Mellitus Affect Key Outcomes in Women Participating in a Diabetes Prevention Program?
5 answers
Women with a history of gestational diabetes mellitus (GDM) do not show significant differences in participation, self-monitoring behavior, achievement of weight loss goals, or cardiometabolic risk reduction compared to women without GDM when participating in diabetes prevention programs. Studies indicate that lifestyle interventions, such as the National Diabetes Prevention Program (NDPP), are effective in promoting weight loss and reducing diabetes risks among women, including those with a history of GDM. Additionally, interventions like intensive lifestyle programs or metformin have been shown to significantly reduce the risk of type 2 diabetes in high-risk women with a history of GDM. Therefore, despite the increased risk associated with GDM, women can successfully participate in and benefit from diabetes prevention programs to achieve weight loss and reduce cardiometabolic risks.
What are the underlying metabolic changes that contribute to metabolic inflexibility in overweight and obese individuals?
5 answers
Metabolic inflexibility in overweight and obese individuals stems from various metabolic alterations. In skeletal muscle, physical inactivity can induce metabolic inflexibility by reducing pyruvate-stimulated respiration, potentially due to decreased phosphatidylethanolamine levels in the mitochondrial membrane. Additionally, obese individuals exhibit reduced maximal fat oxidation (MFO) relative to lean individuals, indicating a diminished capacity to oxidize fat during exercise per unit of metabolically active tissue, highlighting metabolic inflexibility during physical activity. Maternal obesity further exacerbates metabolic inflexibility, as pregnant overweight and obese women demonstrate lower metabolic flexibility compared to lean women, correlating with postprandial inflammation and insulin resistance. These findings collectively underscore the multifaceted nature of metabolic changes contributing to metabolic inflexibility in overweight and obese individuals.
Is cord blood and placental mtdna content correlated?
5 answers
Yes, cord blood and placental mtDNA content are correlated. Research indicates that placental mtDNA content at birth is associated with intelligence in childhood. Additionally, fetal thyroid hormones like FT3 and FT4 are inversely associated with placental mtDNA methylation and positively associated with placental mtDNA content. This suggests a link between fetal thyroid hormones and placental mtDNA content through epigenetic modifications in specific loci of the mitochondrial genome. Therefore, the data supports a correlation between cord blood and placental mtDNA content, highlighting the importance of mitochondrial function in both cord blood and placental tissue for various developmental outcomes.
How does the molecular mechanism of type 2 diabetes differ from that of type 1 diabetes?
5 answers
The molecular mechanisms of type 2 diabetes (T2D) and type 1 diabetes (T1D) differ significantly. T2D is primarily characterized by insulin resistance and β-cell dysfunction, while T1D involves autoimmune destruction of pancreatic β-cells. In T2D, metabolic stress responses like ER stress, oxidative stress, and inflammation play crucial roles in β-cell functional alterations. Additionally, T2D is associated with perturbed insulin secretion and dysregulated gene networks in different islet cell types, affecting processes like mitochondrial function, glycolysis, and cell proliferation. On the other hand, T1D is linked to immunogenetic causes, changes in metabolism, and functional insulin deficiency. Understanding these distinct molecular pathways is essential for precise diagnosis and targeted interventions for both types of diabetes.
How is CCR7 involved in inflammation diseases?
5 answers
CCR7 plays a crucial role in inflammatory diseases by regulating immune cell migration and inflammatory processes. In the context of dendritic cells, CCR7 facilitates their migration to lymph nodes, where they initiate antigen presentation and immune responses. Abnormal expression of CCR7 in dendritic cells can lead to inflammatory diseases due to disrupted cell trafficking. Additionally, CCR7 is implicated in chronic inflammatory conditions like multiple sclerosis, rheumatoid arthritis, and psoriasis, where it contributes to disease progression. Targeting the CCR7 network is proposed as a potential strategy to modulate dendritic cell migration and manage inflammatory diseases effectively. Therefore, understanding the regulatory mechanisms of CCR7 and its ligands is essential for developing therapeutic interventions for inflammatory diseases.
Do saturated fats impair cognitive function?
5 answers
Excess consumption of saturated fatty acids (SFAs) has been linked to impaired cognitive function in various studies. Research suggests that high intake of SFAs can lead to cognitive decline, vascular dementia, insulin resistance, endoplasmic reticulum stress, and mitochondrial dysfunction, all of which are detrimental to cognitive health. Specifically, a higher level of SFAs in plasma has been associated with cognitive decline, while monounsaturated fatty acids (MUFAs) may have a protective effect on cognitive function. Moreover, studies have shown that the highest intake of saturated fat is correlated with an increased risk of cognitive impairment and Alzheimer's disease, emphasizing the negative impact of SFAs on cognitive health. Therefore, reducing the consumption of saturated fats may be beneficial in preserving cognitive function and overall brain health.
What are the potential mechanisms through which sorghum consumption may influence cardiovascular health in humans?
5 answers
Sorghum consumption may influence cardiovascular health in humans through various mechanisms. Firstly, sorghum is rich in bioactive compounds like phenolic acids, flavonoids, and tannins, which act as antioxidants, potentially protecting against inflammation and cancer. Additionally, sorghum consumption can reduce blood cholesterol and glucose levels, benefiting cardiovascular health. Moreover, sorghum's fiber content may further contribute to cardiovascular health by aiding in cholesterol reduction and glucose level management. Furthermore, sorghum consumption has been linked to improved cardiovascular health in animals, suggesting potential benefits for humans that warrant further investigation. Overall, the bioactive components and functional composition of sorghum make it a promising dietary option for promoting cardiovascular health in humans.
What are the benefits and costs of oatmeal intake?
5 answers
Oatmeal intake offers numerous health benefits. Oats are rich in bioactive compounds like β-glucan, avenanthramides, and tocols, which can reduce the risk of cardiovascular diseases, type 2 diabetes, and cancer. Studies show that oat consumption significantly reduces glycosylated hemoglobin A1c, fasting blood glucose, total cholesterol, and LDL cholesterol in diabetic patients, indicating improved glucose control and lipid profiles. Oats also positively impact gut health by increasing beneficial bacterial groups and improving gut permeability, although some individuals with celiac disease may experience worsened symptoms. Additionally, increased oat consumption has been associated with reduced blood pressure and cholesterol levels, further lowering cardiovascular disease risk. However, in a study involving middle-aged individuals, oat intake did not significantly affect blood pressure or serum cholesterol concentrations.
How does sympathetic activation change metabolism?
4 answers
Sympathetic activation plays a crucial role in altering metabolism by influencing energy homeostasis and metabolic control. Studies highlight that sympathetic overactivity is linked to various metabolic conditions like the Metabolic Syndrome, hypertension, diabetes, and obesity. This overactivity can lead to insulin resistance, impaired glucose metabolism, and weight gain, impacting overall metabolic health. Research suggests that interventions targeting central sympathetic drive, such as baroreflex activation therapy, can help regulate blood pressure without negatively affecting metabolic parameters like fasting glucose levels. Additionally, beta-blockers have shown benefits in reducing mortality in patients with hypertension, diabetes, and obesity by modulating sympathetic activity without significant adverse effects on carbohydrate and lipid metabolism.
How does the incidence of type 1 diabetes in children vary across different regions and populations?
4 answers
The incidence of type 1 diabetes in children varies significantly across regions and populations. Globally, the reported incidence rates range from 0.1 in China and Venezuela to as high as 36.8 in Sardinia and 36.5 in Finland, with a more than 350-fold difference. Higher rates are generally observed in higher-income countries, such as Sweden, Norway, Canada, the United Kingdom, and New Zealand. The prevalence of pancreatic islet autoantibodies (iAb) in children and adolescents with type 1 diabetes also varies across different regions, with IA-2A being the most prevalent globally in new-onset cases, showing substantial variation across world regions. Understanding these variations is crucial for early identification, clinical management, and resource allocation to address the increasing global health challenge of childhood diabetes.