Can metastatic breast cancer be asymptomatic?
Answers from top 10 papers
More filters
Papers (10) | Insight |
---|---|
The reported case confirms that bladder metastases from breast cancer tend to occur late after the diagnosis of the primary tumor and, for the first time, points out they can be asymptomatic. | |
52 Citations | Malignant melanoma metastatic to the breast can be diagnosed reliably by fine-needle aspiration cytology, thus avoiding radical and unnecessary surgery. |
Metastatic disease to the intramammary lymph nodes may be the first clinical and/or mammographic sign of breast cancer and may significantly affect prognosis. | |
23 Citations | Although metastatic ovarian cancer to the breast following treatment for ovarian cancer is rare and associated with a poor prognosis, oncology physicians should be prepared to contend with disease metastatic to the breast. |
44 Citations | In patients with nonmetastatic breast cancer, screening for asymptomatic brain metastases cannot currently be justified. |
53 Citations | If true, these results suggest that metastatic disease, like primary breast cancer, may be multiple diseases and that stratification of late stage patients may therefore be required to fully understand breast cancer progression and metastasis. |
19 Citations | Metastatic breast cancer should therefore be suspected in patients with a history of breast cancer and diarrhea of unknown cause that is not accompanied by other symptoms. |
14 Citations | Distinguishing metastatic breast cancer from other types of malignancies can be diagnostically challenging but is important for correct treatment and prognosis. |
21 Citations | While metastatic breast tumors are rarely the initial sign of malignancy, it is important to distinguish a metastasis from primary breast cancer to avoid unnecessary conflicting treatments. |
Metastatic gastrointestinal carcinoma to the breast is a rare lesion but needs to be at least included in the differential diagnosis of breast masses, especially in patients with a history of gastrointestinal cancer. |
Related Questions
What is the difference in mean age at diagnosis between metastatic and non-metastatic breast cancer patients?5 answersThe mean age at diagnosis differs between metastatic and non-metastatic breast cancer patients. Younger age at diagnosis, specifically ≤40 years, is associated with adverse outcomes in breast cancer patients, including higher metastatic rates and poorer survival outcomes. In contrast, older patients, especially those ≥40 years, tend to have a higher 10-year overall survival rate compared to younger patients. Additionally, blood biomarkers related to aging processes have been studied in breast cancer patients, revealing distinct biological profiles that transcend chronological age and impact overall survival. Therefore, age at diagnosis plays a crucial role in determining the prognosis and outcomes of breast cancer patients, with younger patients facing more challenges in terms of metastatic patterns and survival rates.
Does breast cancer usually develop into metastatic invasive bc?4 answersBreast cancer can develop into metastatic invasive breast cancer (BC). Metastasis is a major contributor to high cancer mortality and is usually the endpoint of a series of sequential and dynamic events. Various biological molecules, cells, and signaling pathways are altered in BC, promoting the formation of a pre-metastatic niche (PMN) that provides a suitable environment for tumor cells to colonize and progress into metastases. The development and progression of BC involve a sequential process, from normal to hyperplastic, to in situ, and to invasive and metastatic stages. Over 90% of cancer deaths are caused by invasive and metastatic lesions. Understanding the molecular determinants of BC metastasis could facilitate the development of improved prevention and treatment strategies. Despite advances in breast cancer screening, diagnosis, and treatment, nearly 12% of patients with breast cancer eventually develop metastatic disease.
Can dvt be asymptomatic?5 answersDeep vein thrombosis (DVT) can be asymptomatic, meaning that it does not show any symptoms. Asymptomatic DVTs are incidentally found during diagnostic tests or screenings. Although asymptomatic DVTs were previously considered clinically irrelevant, they are now being treated with anticoagulation for a period of 3 to 12 months. This change in approach has led to a higher incidence of asymptomatic DVTs being detected and managed as cases of DVT. The incidence of asymptomatic calf vein DVT in high-risk surgical patients was found to be 3.06% in one study. Another study reported an incidence of 0.94% asymptomatic DVT after total knee arthroplasty (TKA) with prophylactic antithrombotic therapy. It is important to note that asymptomatic DVTs can still pose a risk and may require treatment, especially in patients with certain risk factors such as a history of DVT or revision surgery.
What is the prevalence of breast cancer in asymptomatic females compared to symptomatic females?5 answersThe prevalence of breast cancer in asymptomatic females compared to symptomatic females varies. Mammographic screening in asymptomatic women has been associated with a reduction in breast cancer mortality and the detection of small asymptomatic tumors, leading to more therapeutic choices and a reduced need for chemotherapy. On the other hand, symptomatic women who self-select for breast cancer evaluation have a higher risk of breast cancer compared to the healthy population. Risk factors such as age and use of estrogen replacement therapy have been found to increase the risk of breast cancer in symptomatic women. However, the risk of breast cancer in symptomatic patients is independent of the specific breast complaint and is primarily related to age. Therefore, further investigations are warranted in symptomatic patients only when risk factors other than breast complaints are present.
What is the incidence with breast cancer metastasis to distinct organs?5 answersBreast cancer has a high incidence of metastasis to various organs. The most common sites of metastasis include the bone, brain, lung, liver, and lymph nodes. Metastasis to the colon is rare but has been reported in some cases. Gastrointestinal involvement, including the stomach and colon, occurs in a small percentage of breast cancer metastases. Metastasis to gynecological organs, such as the ovaries, fallopian tubes, and peritoneum, is also observed in breast cancer patients. Overall, breast cancer can spread to a range of organs, both locally and distantly, leading to secondary tumor formation and worsening prognosis.
Is metastatic breast cancer inoperable?9 answers