Can neurons be grown in a lab?
Answers from top 15 papers
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| Papers (15) | Insight |
|---|---|
| These results demonstrate that motor neurons can differentiate from spinal cord neural precursor cells grown in culture as well as following transplantation into a transected peripheral nerve. | |
| Preparations processed in this way can be studied electron microscopically, in this way rendering fine structural examination of previously identified neurons possible. | |
136 Citations | These results suggest that neurons destined to die in ovo can be rescued when grown in cell culture with myotubes and that under these conditions the neurons develop and express differentiated properties. |
51 Citations | Mature neurons might be resistant to such exposures, but new neurons may be vulnerable. |
36 Citations | Patient-derived neurons from different regions of the brain can be directly grown and differentiated on a brain-on-a-chip device where the disease development, progression and pharmacological treatments can be studied and monitored in real time. |
| It shows that adult motor neurons can be isolated from in vivo models of motor neuron degeneration and evaluated on a single-cell basis. | |
| This can, in part, be overcome by plating neurons into cell culture where all regions of a neuron are made experimentally accessible. | |
28 Citations | We conclude that these differences should be taken into consideration in designing experiments on dorsal root ganglion neurons grown in tissue culture. |
| More importantly, it has been previously demonstrated that MSCs have the capacity to differentiate into neurons and glia in vitro when grown under appropriate conditions. | |
30 Citations | The cultured neurons can be applied in studies involving electrophysiology, signal transduction, neurotransmitter release, or calcium imaging. |
| Furthermore, our findings indicate that they develop over time and are not present in neurons that are grown in culture for less than 10 days. | |
| These results show that antibodies can be used as substrates for the culture of mature neurons. | |
| The co-culture can be easily maintained for >3 months without significant loss of low density neurons, thus facilitating the morphological and physiological study of these neurons. | |
48 Citations | Because they are rich in functional dopaminergic neurons, these cultures will be a useful tool for studying various properties of dopaminergic neurons. |
40 Citations | A pure population of viable neurons can be obtained easily using gradients of Percoll. |
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