scispace - formally typeset
Search or ask a question

Answers from top 6 papers

More filters
Papers (6)Insight
VEGF may increase some sperm motility parameters, but not survival, in a concentration-dependent manner in vitro.
In conclusion, the effects of sperm dose on fertilization rate and on accessory sperm count in sows were small and nonsignificant, indicating only small effects of sperm dose on the functioning of the sperm reservoir in the sow.
This method can not only minimize damage to the sperm structure, but also increase the effectiveness of selection.
The negative impact of age, BMI and coffee intake on sperm quality could be compensated if patients had a high ejaculation frequency and shorter periods of sexual abstinence. Combinations of adverse lifestyle factors could have a detrimental impact on sperm, not only in terms of motility and sperm count but also in terms of sperm head vacuolization.
This approach has tremendous benefits for men who have difficulty producing sperm and for those with low and declining sperm counts.
Selective attachment of functionally superior sperm to OEC is likely important during sperm reservoir formation in vivo and may be exploitable in vitro as a method to isolate high-quality sperm for clinical procedures.

See what other people are reading

What are the current Non-Hormonal male contraception?
10 answers
Current non-hormonal male contraception research is focused on innovative strategies targeting various aspects of sperm function and production, aiming to provide reversible and effective methods of contraception. Despite the historical reliance on condoms and vasectomy for male contraception, there is a growing interest in developing alternatives that can offer temporary fertility control without the permanent effects of surgical options or the lower efficacy of barrier methods. Recent advancements have identified several promising targets for non-hormonal male contraception. These include specific enzymes, ion channels, and transmembrane transporters that are crucial for sperm motility and fertilization. Notable examples are enzymes like PP1γ2 and GAPDHS, ion channels such as CatSper and KSper, and transporters including sNHE and ATP1A4, which have been identified as potential druggable targets due to their indispensable roles in sperm function. Additionally, the identification of reproductive tract-specific genes associated with male infertility has opened new avenues for targeted drug development, leveraging technologies like CRISPR and proteolysis targeting chimeras (PROTACs) to potentially inhibit sperm production or function. One innovative approach involves the use of an alpha-1-adrenoreceptor antagonist, administered daily to induce reversible aspermia, azoospermia, or severe oligozoospermia, demonstrating a novel mechanism for non-hormonal male contraception. Furthermore, the exploration of genes and proteins specifically expressed in the male reproductive tract has highlighted potential targets for contraception, with phenotypes ranging from disrupted spermatogenesis to abnormal sperm motility and morphology, indicating their viability for developing effective contraceptives. Despite these promising developments, the transition from preclinical research to clinically approved non-hormonal male contraceptives faces challenges, including the need for rigorous safety, efficacy, and reversibility evaluations, as well as the establishment of clear guidelines for clinical trials. The collaboration among academia, industry, and regulatory agencies is crucial to overcome these hurdles and bring these innovative contraceptives to market.
Artificial insemination in humans is minimally invasive?
4 answers
Artificial insemination in humans is considered minimally invasive. It is a low-cost method that is easily acceptable for female hormone treatment, making it a valuable option for infertile couples. Techniques like sperm washing, swim-up, and density gradient centrifugation are commonly used to prepare spermatozoa for artificial insemination, focusing on selecting the best quality sperm for higher success rates. Minimally invasive surgery plays a crucial role in assisted reproductive technology by enabling the diagnosis and treatment of various reproductive abnormalities with reduced invasiveness and fewer complications. Overall, artificial insemination procedures aim to be minimally invasive while maximizing the chances of successful fertilization and pregnancy, making them a preferred choice for many couples facing infertility issues.
Procedure for artificial insemination in humans?
5 answers
The procedure for artificial insemination in humans involves depositing sperm into the female reproductive organs to facilitate fertilization. This method aims to increase gamete density at the site of fertilization, with techniques refined over time for better outcomes. The history of artificial insemination dates back centuries, with modern techniques adapted from cattle breeding practices. Success depends on factors like choosing the correct insemination timing, using quality sperm, proper handling, and selecting the appropriate method, such as using washed motile spermatozoa. The preparation of sperm is crucial, and advancements in this area have renewed interest in artificial insemination for subfertile women worldwide.
Artificial insemination in humans is least invasive?
5 answers
Artificial insemination (AI) in humans is considered minimally invasive compared to other assisted reproductive techniques like in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). AI is commonly used for unexplained infertility and male subfertility, serving as the initial treatment choice before resorting to more invasive procedures. The process involves selecting ejaculated spermatozoa through techniques like swim-up, density gradient centrifugation, and sperm washing to enhance fertilization potential. AI's minimally invasive nature, cost-effectiveness, and acceptability make it a preferred option for cases of cervical factor subfertility, mild-moderate male subfertility, and unexplained infertility. Overall, AI in humans is a relatively non-invasive and accessible method in assisted reproduction, offering a viable solution for various fertility challenges.
What is the scientific rationale behind incubating total cholesterol samples at 37°C?
5 answers
The scientific rationale behind incubating total cholesterol samples at 37°C lies in the structural transition and configurational changes in the aliphatic chain of the cholesterol molecule. Additionally, incubating samples at this temperature can induce capacitation-like changes in sperm, affecting their quality and viability. Furthermore, maintaining a stable temperature during storage is crucial for preserving the integrity of blood specimens, as fluctuations can impact the stability of the specimen and lead to changes in cholesterol levels. Therefore, incubating total cholesterol samples at 37°C ensures that any structural transitions or changes in the cholesterol molecule are accurately reflected in the analysis, contributing to the reliability of cholesterol level measurements.
What is media for enrichment S. epidermidis?
4 answers
Media for enrichment of S. epidermidis includes solid media with pre-enrichment, which has shown to be more efficient for optimal bacterial isolation from seminal fluid. Additionally, the invention of an enrichment culture medium containing various components like beef liver powder, malt extract powder, and yeast extract powder plays a role in transporting and enriching microorganisms. Furthermore, advancements in media enrichment technology, such as sound media enrichment, are crucial for multimedia communication progress, covering areas like signal processing for audio enrichment and speech quality assessment. Moreover, the application of media enrichment in communication networks involves providing subtitle support in video calls and audio language translation support, utilizing technologies like IMS network and Session Initiation Protocol.
What are the key factors or parameters that affect drone parameter analysis?
5 answers
Drone parameter analysis is influenced by various key factors. These include flight altitude, overlap and sidelap percentages, which impact the accuracy of topographic maps derived from UAV images. Additionally, the number of rotors, maximum flight time, wingspan, weight, and autonomous flight capability significantly affect drone prices. Moreover, in the context of solar-powered UAVs, parameters such as minimum and maximum altitudes for flight, gliding and climbing angles, design speed, and start times for gliding and climbing are crucial for storing potential energy through climb flight. Furthermore, in the assessment of drone sperm quality, motility index scores, total motility percentages, and velocity parameters play a vital role in determining fertility potential and colony health.
How long is sperma is affected from smoking?
5 answers
The impact of smoking on sperm can have long-lasting effects. Research indicates that smoking can lead to changes in both the number and quality of sperm, with detrimental effects on sperm viability, motility, and morphology. Studies have shown that exposure to cigarette smoke during the gestational/weaning period can cause long-term defects in male offspring fertility, affecting spermatogenesis, germ cell development, and sperm quality. Additionally, smoking has been linked to decreased sperm motility and count, with continued smoking exacerbating these effects over time. While some studies suggest that the impact of smoking on sperm parameters may be reversible after cessation, the detrimental effects on fertility can persist and even influence the outcomes of assisted reproduction techniques like IVF and ICSI.
What are fecondation in vitro technique?
5 answers
In vitro fertilization (IVF) techniques involve fertilizing an egg with sperm outside the body. IVF can be performed in different ways, such as natural cycle IVF, where fertilization occurs in the woman's natural monthly cycle. For women with endometriosis, IVF may be recommended after other treatments like inseminations have failed, especially in cases of ovarian or deep endometriosis. To increase the success rate of pregnancy, methods like pre-treating with GnRH agonists or estroprogestatives before ovarian hyperstimulation can be employed. Additionally, a method involving implanting embryos into the uterus after preparing the endometrium with peripheral blood mononuclear cells has been proposed to reduce immune rejection and enhance pregnancy success. These various IVF techniques cater to different infertility conditions and contribute to individualized fertility treatments.
What is the literature on automated assessment for STIGs and SCAPs?
5 answers
The literature on automated assessment for STIGs and SCAPs is diverse and covers various aspects. Automated assessment tools, such as those utilizing AI or static analysis, are commonly used in software engineering for program repair and in software security for vulnerability identification. These tools aim to provide scalable feedback for learning and accreditation purposes in computing courses at tertiary institutions. Additionally, there are methods for managing security vulnerabilities and threats in monitored systems, involving continuous monitoring, threat data storage, and security event analysis. Furthermore, assessment engines are developed to evaluate physical activities, utilizing classifiers to determine performance scores based on historical data and video content. Overall, the literature emphasizes the importance of automated tools in enhancing security and performance assessment processes.
How owners conduct curfews in every boar?
5 answers
Owners conduct curfews for boars by implementing temporary administrative police measures, restricting the movement of inhabitants for a specified period. In Hawaii, wild pigs, an invasive species, pose challenges due to their abundance and impact on native ecosystems. The history of wild pigs in Hawaii reveals their Polynesian ancestry and subsequent interbreeding with various domestic and wild pig species. Studies show that while pig hunting is common in Hawaii, non-hunters often desire a decrease in pig abundance, highlighting the need for localized management approaches. Understanding the cultural significance of pigs in Hawaii is crucial for effective wildlife management, requiring a balance between conservation efforts and local values. The legal aspects of animal law, including regulations on curfews for certain diseases, also play a role in managing boars and other animals.