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Finally, the mesenchymal stem cells seems to be hypoimmunogenic and thus allogenic mesenchymal stem cells transplantation is possible.
Open accessJournal ArticleDOI
George Kolios, Yuben Moodley 
01 Jan 2013-Respiration
298 Citations
Stem cells can be used in cellular therapy to replace damaged cells or to regenerate organs.
Among all adult stem cell types, umbilical cord mesenchymal stem cells (UCMSCs) can be collected easily and does not harm newborns and the mothers.
Therefore, mesenchymal stem cells can be considered as an ideal source for replacing lost cells in degenerative diseases like Parkinson's.
Moreover, since the stem cells were obtained from peripheral blood, it can be concluded that MSC circulate among mobilized peripheral blood stem cells and can engraft in bone marrow after allogeneic transplantation.
On the basis of our analysis, we conclude that patients should not be asked to donate their fresh embryos to stem cell research.
Open accessJournal ArticleDOI
András Simon, Jonas Frisén 
09 Mar 2007-Cell
16 Citations
(2007) propose that the progeny of stem cells, called transit-amplifying progenitor cells, are able to replace lost stem cells.
Journal ArticleDOI
Jane E. Visvader, Hans Clevers 
127 Citations
'Professional' stem cells may also co-exist with facultative stem cells, which are more specialized daughter cells that revert to a stem cell state under specific tissue damage conditions.
Human embryonic stem (hES) cells and the recently established human induced pluripotent stem (hiPS) cells represent potentially unlimited sources of donor-free RBCs for blood transfusion, as they can proliferate indefinitely in vitro.
Moreover, adult stem cells can be used in autogenous form.

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