Can you take glutathione and zinc together?
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| Papers (11) | Insight |
|---|---|
122 Citations | The authors present a new model of zinc currents and zinc toxicity that offers expanded opportunities for zinc-selective therapeutic chelation interventions. |
12 Citations | Moreover, we have demonstrated that kinetic studies using stable isotopes of zinc can provide novel information on exchangeable zinc pools in clinical situations. |
194 Citations | Glutathione levels can be increased by administration of cysteine or of glutathione, but these approaches are not entirely satisfactory. |
90 Citations | The results indicate that zinc not only induces metallothionein, but also increases protective enzyme activities and glutathione content, which would tend to inhibit lipid peroxidation and suppress mercury toxicity. |
10 Citations | These studies suggest that the hepatoprotective effect of zinc against bromobenzene toxicity does not involve altered binding of the reactive toxic metabolite to glutathione or metallothionein, but it may be mediated by the inhibitory effect of zinc on the microsomal cytochrome P-450-dependent drug metabolizing system. |
| Glutathione stimulates the accumulation of phytochelatins in cadmium treated cells, indicating that availability of glutathione can limit synthesis of these peptides. | |
| Zinc supplementation can also alleviate the degree of mucositis and dermatitis. | |
| Apparently, zinc release does not involve direct access of glutathione disulfide to the inner coordination sphere of the metals. | |
49 Citations | The mode of action of zinc could occur via free radical scavenging by zinc-induced metallothionein and/or by processes related to cytochrome P-450 and glutathione peroxidase, since these were also found to be sensitive to zinc supplementation levels of the culture medium. |
| Such a mechanism of metal release would link the control of the metal content of metallothionein to the cellular glutathione redox status and raises important questions about the physiological implications of this observation with regard to a role of glutathione in zinc metabolism and in making zinc available for other biomolecules. | |
11 Citations | It is concluded that the cell lines tested can use other sources of cys for glutathione synthesis. |
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