Do Axolotls have a spinal cord?
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It is suggested that most VT neurons project descending axons to the cervical spinal cord. | |
32 Citations | We also suggest that other species are likely to have a small-celled area of red nucleus projecting to the spinal cord. |
37 Citations | These neurochemical and angiogenic substances are undoubtedly involved in some manner in the ability of axons in a transected spinal cord to grow at 1 mm/day and apparently make appropriate connections with distal spinal cord target tissue. |
These results indicate that successful growth of axons from the cortex to the spinal cord depends on the developmental age of the tissue terrain (the spinal cord and/or the interface between cortex and spinal cord explants), and to a lesser extent on the developmental state of the cortical neurons, and that axon growth between cortex and spinal cord can be enhanced by exogenous neurotrophins. | |
95 Citations | Growth of the host dorsal roots into transplants indicates that fetal spinal cord tissue permits regeneration of adult axotomized neurons that would otherwise be aborted at the dorsal root/spinal cord junction. |
24 Citations | We conclude that few brainstem nuclei can directly affect the whole spinal cord, whereas many nuclei may have an impact on its most rostral regions; here we have found labelled spinal interneurons with long descending axons that reach the most caudal cord levels. |
120 Citations | Thus the long ascending and descending myelinated fibre tracts of the adult spinal cord provide a permissive environment for the rapid growth of axons from embryonic donor neurons from a region not normally projecting to the spinal cord. |
184 Citations | Spinal cord mechanisms are possibly involved. |
24 Citations | Thus unmyelinated axons predominate in the white matter of the rat sacral spinal cord. |
We find that the acceleration of the cell cycle is necessary and sufficient to drive the outgrowth of the regenerating spinal cord in axolotls. | |
These results suggest that alginate might provide a permissive microenvironment for elongation of spinal cord axons. | |
12 Citations | These results are in general agreement with observations on spinal cord of different animal species. |