Do you have to lose your mucus plug before a membrane sweep?
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| Papers (10) | Insight |
|---|---|
29 Citations | PCL layer dehydration reduces mucociliary clearance (MCC), leading to airway obstruction (reduced airflow and inflammation due to pathogen invasion) with mucus plug formation. |
| This mucus plug can cause collapse of the lung and ill consequences. | |
| Mucus plugs are a plausible mechanism of chronic airflow obstruction in severe asthma, and EPO-generated oxidants may mediate mucus plug formation. | |
14 Citations | Results show that, the maximum wall shear stress remarkably changes right prior to the rupture of the mucus plug. |
30 Citations | Fluid dynamics of mucus plug rupture is important to understand mucus clearance in lung airways and potential effects of mucus plug rupture on epithelial cells at lung airway walls. |
19 Citations | Mucus secretions of the intestine may contribute to plug formation in CF, through several mechanisms acting alone or simultaneously. |
| propose a unique function for mucus, to trap phage to intersect and destroy invading bacteria before they reach the mucus-encapsulated tissue. | |
| The observations suggest that mucus synthesis occurs in the supranuclear region and that the mucus is passed through the goblet before discharge. | |
| Mucus secretion may therefore be initiated by the interaction of mucus-releasing stimuli with fucosyl or galactosyl residues of specific membrane receptors. | |
15 Citations | It is proposed that the mucus globule membrane is the unidentified component and that the relative amount of the membrane, and hence the size of the mucus globule, is the factor that determines the viscosity of mucus. |
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