Does Astrazeneca vaccine use RNA?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
15 Citations | Therefore, RNA adjuvants have broad applicability and can be used with all conventional vaccines to improve vaccine efficacy qualitatively and quantitively. |
| RNA, on the other hand, is readily taken up and expressed by DC, making it an alternative vaccine candidate. | |
79 Citations | FROM THE CLINICAL EDITOR The use of self-amplifying replicon RNA (RepRNA) to increase vaccine antigen payloads can potentially be useful in effective vaccine design. |
| Preclinical and clinical applications of self-amplifying RNA viral vectors have proven efficient for vaccine development and due to the presence of RNA replicons, amplification of RNA in host cells will generate superior immune responses with significantly reduced amounts of RNA delivered. | |
14 Citations | We therefore suggest that RNA-transfected DC vaccine efficacy could be improved by the use of mRNA targeted to the proteasome. |
21 Citations | These results illustrate that for an RNA-based vector the RNA sequence of the antigen can have profound and unforeseen consequences on vaccine behaviour. |
183 Citations | These preclinical studies demonstrate that an RNA tumor antigen vaccine strategy has potential application for human cancer treatment and prevention. |
59 Citations | RNA are potential vaccine adjuvants for immune enhancement against cancer and provide a benefit for vaccinations. |
20 Citations | The RNA initiates limited replication of a genetically defined, live-attenuated vaccine virus in the tissues of the vaccine recipient, thereby inducing a protective immune response. |
74 Citations | This demonstrates that DNA vaccine potency may be augmented by the incorporation of RIG-I-activating immunostimulatory RNA into the vector backbone. |