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Does Clomid block all estrogen receptors? 

Estrogen receptor
Estrogen receptor beta
Receptor
Hypothalamus
Estrogen

Answers from top 10 papers

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Papers (10)Insight
Journal Article•DOI
Estrogen and β-amyloid toxicity: Role of integrin and PI3-K
Chiarella Bozzo, Francesca Graziola, Annalisa Chiocchetti, Pier Luigi Canonico 
01 Oct 2010-Molecular and Cellular Neuroscience
15 Citations
Estrogen receptor antagonist does not hinder estrogen protection.
Journal Article•DOI
Studies on the Role of Sex Steroids in the Feedback Control of Gonadotropin Concentrations in Men. II. Use of the Estrogen Antagonist, Clomiphene Citrate
Stephen J. Winters, John J. Janick, D. Lynn Loriaux, Richard J. Sherins 
01 Feb 1979-The Journal of Clinical Endocrinology and Metabolism
100 Citations
We theorized that this approach might provide an opportunity to evaluate the pure androgenic component of testosterone, independent of its aromatization to estradiol, since the estrogen antagonist, clomiphene, would block estrogen-mediated effects.
Open access•Journal Article•DOI
Clomiphene citrate administration to normogonadotropic subfertile men: blood hormone changes and activation of acid phosphatase in seminal fluid.
L. Rönnberg, Pirkko Vihko, E. Sajanti, Reijo Vihko 
01 Dec 1981-International Journal of Andrology
60 Citations
This is suggested to be a result of the blocking of testicular oestradiol receptors by the estrogen antagonist, clomiphene.
Journal Article•DOI
Alterations induced by clomiphene in the concentrations of oestrogen receptors in the uterus, pituitary gland and hypothalamus of female rats
Eli Y. Adashi, A. J. W. Hsueh, S. S. C. Yen 
01 Dec 1980-Journal of Endocrinology
24 Citations
The findings have confirmed earlier reports on the long-term uterotrophic effect of Clomid and have suggested that under these long-term, in-vivo conditions, Clomid acts in the uterus and pituitary gland as a long-acting oestrogen characterized by prolonged retention of oestrogen receptors in the nucleus and delayed, but otherwise effective, replenishment of the oestrogen receptors in the cytoplasm.
Journal Article•DOI
Three nuclear and two membrane estrogen receptors in basal teleosts, Anguilla sp.: Identification, evolutionary history and differential expression regulation.
Anne Gaëlle Lafont, Karine Rousseau, Jonna Tomkiewicz, Sylvie Dufour 
01 Sep 2016-General and Comparative Endocrinology
32 Citations
This first comparative study of the five teleost estradiol receptors provides bases for future investigations on differential roles that may have contributed to the conservation of multiple estrogen receptors.
Open access•Journal Article•DOI
Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line.
Azam Mohamadi, Mahmoud Aghaei, Mojtaba Panjehpour 
01 Feb 2018-Research in Pharmaceutical Sciences
12 Citations
Treatment with antagonist confirmed that up-regulation of these receptors is mediated by estrogen receptor.
Journal Article•DOI
Sensitisation of pituitary cells to luteinising hormone releasing hormone by clomiphene citrate in vitro.
Aaron J. W. Hsueh, Gregory F. Erickson, S. S. C. Yen 
04 May 1978-Nature
60 Citations
On the other hand, the observation that Clomid stimulates uterine growth is suggestive of an oestrogenic action8,9.
Journal Article•DOI
Effects of estrogenic compounds on human spermatozoa: evidence for interaction with a nongenomic receptor for estrogen on human sperm membrane
Michaela Luconi, Lorella Bonaccorsi, Gianni Forti, Elisabetta Baldi 
10 Jun 2001-Molecular and Cellular Endocrinology
67 Citations
These results indicate that the two estrogens act as pharmacological agonists of the membrane estrogen receptors of human spermatozoa.
Journal Article•DOI
Sensitisation of pituitary cells to luteinising hormone releasing hormone by clomiphene citrate in vitro.
Aaron J. W. Hsueh, Gregory F. Erickson, S. S. C. Yen 
04 May 1978-Nature
60 Citations
We show here, using cultured pituitary cells as a model system, the possible antioestrogenic and oestrogenic effects of Clomid on LH release in vitro, and demonstrate that Clomid, like oestradiol-17β, increases the responsiveness of gonadotrophs to LHRH in vitro.
Open access•Journal Article•DOI
Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line.
Azam Mohamadi, Mahmoud Aghaei, Mojtaba Panjehpour 
01 Feb 2018-Research in Pharmaceutical Sciences
12 Citations
However, these effects were partially restored by treatment with antagonist suggesting that such effects are mediated by estrogen receptors.

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