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Does Glutathione cause loose motion? 

Glutathione reductase
Efflux
Glutathione
Oxidative stress
Glutathione peroxidase

Answers from top 14 papers

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Papers (14)Insight
Open access•Journal Article•DOI
Nutritional potentials inZoanthus sociathus (Coelenterata, Anthozoa)
R. K. Trench
01 Sep 1974-Helgoland Marine Research
72 Citations
A similar behaviour may be elicited with reduced glutathione.
Open access•Journal Article•DOI
Sinusoidal efflux of glutathione in the perfused rat liver. Evidence for a carrier-mediated process.
Murad Ookhtens, K Hobdy, M C Corvasce, T. Y. Aw, Neil Kaplowitz 
01 Jan 1985-Journal of Clinical Investigation
130 Citations
The results support our hypothesis that sinusoidal efflux of glutathione is near saturation (approximately equal to 80% of Vmax) at normal (fed and fasted) liver glutathione concentrations.
Open access•Journal Article•DOI
Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia.
R P Elferink, Roelof Ottenhoff, W. Liefting, J de Haan, Plm Jansen 
01 Aug 1989-Journal of Clinical Investigation
163 Citations
These results suggest that the canalicular transport system for glutathione and glutathione conjugates is severely impaired in TR- rats, whereas sinusoidal efflux is unaffected.
Open access•Journal Article•DOI
Glutathione and its antiaging and antimelanogenic effects.
Sinee Weschawalit, Siriwan Thongthip, Phanupong Phutrakool, Pravit Asawanonda 
27 Apr 2017-Clinical, Cosmetic and Investigational Dermatology
61 Citations
Overall, glutathione in both forms are well tolerated.
Journal Article•DOI
Thiol and redox reactive agents exert different effects on glutathione metabolism in HeLa cell cultures
Björn Hultberg, Anders F. Andersson, Anders Isaksson 
01 May 1999-Clinica Chimica Acta
36 Citations
Possibly, the thiol reactive agents decrease the concentration of glutathione, thereby stimulating further synthesis of glutathione, since glutathione synthesis is subject to feedback regulation by glutathione on gamma-glutamylcysteine synthase.
Open access•Journal Article•DOI
Role of glutathione in stabilization of nitric oxide during hypertension developed by inhibition of nitric oxide synthase in the rat.
Olga Pechanova, Misato Kashiba, Masayasu Inoue 
01 Oct 1999-Japanese Journal of Pharmacology
In NO-deficient hypertensive rats, the results are indicative of a decrease in glutathione synthesis and a stabilizing role of glutathione.
Journal Article•DOI
Importance and regulation of hepatic glutathione.
Laurie D. DeLeve, Neil Kaplowitz 
01 Nov 1990-Seminars in Liver Disease
273 Citations
In addition, glutathione may be consumed in conjugation reactions.
Journal Article•DOI
Amlodipine and glutathione cycle in hypercholesterolaemia.
Isil Mutaf, Sara Habif, Nevbahar Turgan, Zuhal Parildar, Dilek Özmen, Oya Bayindir, Ayşegül Uysal 
01 Oct 2004-Acta Cardiologica
However, this drug does not seem to affect the glutathione redox cycle in the aortic tissue.
Journal Article•DOI
Vitamin E and red blood cell glutathione
Ciro Costagliola, T Libondi, M Menzione, E Rinaldi, G Auricchio 
01 Aug 1985-Metabolism-clinical and Experimental
52 Citations
These findings could be explained by an increase of glutathione synthesis brought about by the stimulation of glutathione synthetase activity.
Open access•Journal Article•DOI
Manipulation of glutathione stores in rat hepatic stellate cells does not alter collagen synthesis
Jacquelyn J. Maher, Brent A. Neuschwander-Tetri 
01 Sep 1997-Hepatology
35 Citations
They demonstrate that the mechanism of this resistance does not involve glutathione.
Open access•Journal Article•DOI
Depletion of glutathione from brain cells in hyponatremia
Edward C. Clark, Darbbie Thomas, Jane E. Baer, Richard H. Sterns 
01 Feb 1996-Kidney International
25 Citations
This suggest that osmotic depletion of glutathione is not due to cellular efflux of intact glutathione.
Journal Article•DOI
Calorimetric determination of the micro ionization constants of glutathione.
David L. Vander Jagt, Lee D. Hansen, Edwin A. Lewis, Liang-Po B. Han 
01 Nov 1972-Archives of Biochemistry and Biophysics
The data suggest that glutathione has no unusual intramolecular interactions.
Journal Article•DOI
Blood glutathione as a measure of exposure to toxic compounds
P. Di Simplicio, Piero Dolara, Maura Lodovici 
01 Oct 1984-Journal of Applied Toxicology
Blood glutathione is not a good measure of organ glutathione stores when dealing with indirect‐acting glutathione‐depleting substances.
Journal Article•DOI
Glutathione synthesis and glutathione redox pathways in naphthalene cataract of the rat.
William B. Rathbun, Ann M. Holleschau, Debra L. Murray, Anita Buchanan, Shoichi Sawaguchi, Robert V. Tao 
01 Jan 1990-Current Eye Research
26 Citations
Hence, glutathione loss cannot be explained by a damaged glutathione synthesis system.

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