Does ibuprofen have copper in it?
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125 Citations | Despite the high amount ionised, ibuprofen appears to be well absorbed and it can be classified as a highly permeable drug. |
45 Citations | Ibuprofen, like other NSAIDs, has an identifiable and in some instances a significant side-effect profile which may include gastrointestinal bleeding. |
36 Citations | The results, however, indicated a lattice modification of ibuprofen during processing which we think occurred at the surface. |
| The results, obtained determining ibuprofen and related compounds by CEC, showed the selectivity and efficiency of the method. | |
| Our results lead to a new interpretation of the experimental conditions for producing Form II of racemic ibuprofen and remove racemic ibuprofen from the set of crystalline ... | |
| We conclude that the method described here is ideal for therapeutic monitoring of ibuprofen. | |
39 Citations | Site marking experiments with warfarin and ibuprofen indicated that copper complexes bind at site II of the protein. |
78 Citations | These results indicate that the bioinversion of R(–)ibuprofen administered orally is mainly systemic. |
176 Citations | Although an excellent safety profile characterized ibuprofen in this study, the absence of ibuprofen-associated toxicity may have been secondary to poor rectal absorption of the drug. |
25 Citations | Aluminum metal cation might have interacted to form a complex through the carboxyl and carbonyl groups of ibuprofen. |
| This was attributed to the weakly acidic nature of Ibuprofen. | |
141 Citations | It is more potent than ibuprofen. |
| A rapid, sensitive and specific procedure for determination of ibuprofen has been developed. | |
| Ibuprofen formulations were bioequivalent. | |
73 Citations | The presented data offer a new explanation for the anti-inflammatory effect of ibuprofen. |
38 Citations | Data obtained in this work suggest that the designed ethosomal ibuprofen gel could be further investigated in humans for its antipyretic effect. |
Related Questions
Is ibuprofen soluble in water?4 answersIbuprofen, a nonsteroidal anti-inflammatory drug (NSAID), exhibits low solubility in water. Various studies have explored methods to enhance its solubility. One approach involves forming inclusion complexes with β-cyclodextrin, which has shown improved solubility in aqueous media compared to pure ibuprofen. Another study focused on creating amorphous ternary systems with polyvinylpyrrolidon and β-cyclodextrin, resulting in a stable and water-soluble system that significantly increased ibuprofen's release rate and solubility in water. Additionally, the synthesis of ibuprofen-based ionic liquids (ILs) demonstrated enhanced aqueous solubility compared to neutral ibuprofen and its salt form, sodium ibuprofen. These findings collectively suggest that while ibuprofen has inherent low solubility in water, various strategies such as complex formation and ionic liquid synthesis can effectively enhance its solubility in aqueous environments.
Where is copper used?4 answersCopper finds diverse applications across various fields. It is extensively utilized in electrical, light industry, machinery manufacturing, transportation, construction, national defense, and information and communication sectors. In nurseries, copper is used as a fungicide and fertilizer for seedlings, with specific soil and irrigation requirements for optimal growth. Moreover, copper is an essential nutrient for plants, animals, and humans, playing a crucial role in protein synthesis, although excess copper can be harmful to health. The antimicrobial properties of copper are harnessed in medical settings, industrial equipment, and plumbing systems to prevent and control biofilm formation, showcasing its versatility and effectiveness in various applications. Additionally, copper is valued in analytical and industrial fields for its thermal and electrical properties, leading to the development of innovative sensors for environmental, technological, and medical purposes.
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