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Stem cell transplant may benefit select patients.
Carefully selected patients receiving an autologous stem cell transplant for treatment of myeloma can be managed with a brief initial hospitalization and outpatient follow-up, with low morbidity and mortality.
This procedure is substantially less costly than its counterpart, using in‐hospital myeloablative conditioning regimens, and it may represent another approach in the management of patients requiring an allogeneic stem cell transplant.
These studies found that the key cost drivers appear to be hospitalization length of stay related to initial chemotherapy, relapse of disease, and bone marrow transplant (BMT) and peripheral blood stem cell transplant (PBSCT).
We advocate that Medicare should cover the cost of all immunosuppressive therapy for all solid organ transplant recipients who cannot afford to pay.
The results from this prospective study demonstrate that there is a significant financial and time requirement on the part of the caregiver when a family member or significant other is hospitalized for an autologous stem cell transplant.
Open accessJournal ArticleDOI
Stefan O. Ciurea, Ulas D. Bayraktar 
01 Mar 2015-Blood Reviews
41 Citations
Haploidentical stem cell transplantation (HaploSCT) is an attractive option for patients requiring a hematopoietic stem cell transplant who do not have an HLA-matched donor, because it is cheaper, can be performed faster, and may extend transplantation to virtually all patients in need.
These better outcomes should encourage the treating physician to consider stem-cell transplant at an earlier stage of disease.
Peripheral blood stem cell collection is an effective approach to obtain a hematopoietic graft for stem cell transplantation.
We conclude that in a clinically relevant low-cell-dose unconditioned transplant model, stem cells home to the marrow efficiently, contribute to both short- and long-term hematopoiesis, and, once engrafted, respond to stress effectively.

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