scispace - formally typeset
Search or ask a question

How do antioxidants affect the aging process? 

Best insight from top research papers

Antioxidants play a crucial role in the aging process by neutralizing free radicals and reducing oxidative stress . Free radicals, which are produced as by-products of metabolic processes, can damage DNA, lipids, and proteins, leading to various age-related diseases . Antioxidants break down free radicals and remove them from the body, delaying aging and reducing the risk of age-related diseases . Consuming antioxidant-rich foods, such as fruits, vegetables, and certain dietary supplements, can provide the body with the necessary antioxidants to combat oxidative stress and promote healthy aging . Additionally, antioxidants have been shown to downregulate inflammatory pathways and improve immune function, further contributing to the anti-aging process . Overall, antioxidants have a positive impact on cellular senescence, aging, and age-related diseases by inhibiting oxidative and inflammatory pathways .

Answers from top 4 papers

More filters
Papers (4)Insight
Antioxidants neutralize and scavenge free radicals, which are thought to be one of the main causes of aging by damaging biomolecules.
Antioxidants break down free radicals, remove them from the body, and delay aging. Telomere shortening by free radicals is directly linked with aging and age-related diseases.
Book ChapterDOI
09 Jun 2023
Antioxidants contribute to antiaging by preventing oxidative stress at the cellular level and downregulating genes related to inflammatory pathways.

Related Questions

Antioxidants and skin?5 answersAntioxidants play a vital role in protecting the skin from oxidative damage caused by reactive oxygen species (ROS). Topically applied antioxidants are important in preventing and reducing the severity of UV-induced skin damage and aging. The use of antioxidants in skincare regimens is crucial for preventing and repairing age-related damage. Antioxidants can affect intracellular signaling pathways involved in skin damage, protect against photodamage, prevent wrinkles, and reduce inflammation. The skin is continually exposed to chemical toxicity, and antioxidants help prevent oxidative damage to cells and tissues. However, an excess of free radicals can cause structural or functional damage to cellular macromolecules, leading to perturbations in metabolism, functional impairment, necrosis, or apoptosis. More research is needed to understand the impact of physiologic doses of antioxidants obtained from whole foods on skin health and overall health.
What are antioxidants?4 answersAntioxidants are substances that can delay or prevent oxidative damage to cells. They are found in various foods, including fruits and vegetables. Antioxidants work by inhibiting oxidation processes and protecting cellular components from damage caused by free radicals. They can be natural or synthetic compounds, such as vitamins C and E, polyphenols, and carotenoids. Antioxidants have been studied for their potential health benefits, including reducing the risk of diseases like cancer, heart disease, and stroke. However, the effectiveness of antioxidant supplements in preventing diseases is still debated, as some clinical trials have shown no significant effects or even potential harm. Antioxidants are also used as food additives and in the cosmetic industry to prevent degradation.
What are the effects of antioxidants on premature aging in skin care?5 answersAntioxidants have been shown to have beneficial effects on premature aging in skin care. They can protect the skin from damage caused by oxidation and prevent premature aging. Antioxidants, such as polyphenols, have been found to have antioxidant, anticarcinogenic, and neuroprotective effects when taken into the body in appropriate amounts. Reactive oxygen and nitrogen species (ROS/RNS), which contribute to aging processes, can be neutralized by antioxidants, thereby limiting damage to the skin. Combining natural antioxidants in skin care products can have a synergistic effect, resulting in greater overall benefits for the skin. In a clinical trial, the antioxidant SOD was found to significantly increase total antioxidant status (TAS), decrease transepidermal water loss (TEWL), and improve skin dryness in premature skin aging. These findings suggest that antioxidants can play an important role in preventing and reducing premature aging in the skin.
What are the effects of antioxidants on skin care?4 answersAntioxidants have various effects on skin care. They can improve skin health and youthfulness by combating oxidative stress and reducing the accumulation of free radicals. Antioxidants can also enhance the skin barrier function, increase hydration, and reduce inflammation and itching in skin conditions such as atopic dermatitis. Additionally, antioxidants from marine sources have been found to be effective in treating skin disorders and improving skin health. Incorporating antioxidants into skincare products can activate cells, scavenge free radicals, tighten skin, reduce wrinkles, promote growth of skin cells, and improve skin elasticity. Overall, antioxidants play a crucial role in protecting the skin from damage, promoting its health and appearance, and preventing skin disorders.
What is antioxidant effective?4 answersAntioxidants are effective in protecting cells from free radicals and oxidative damage. They have been shown to have various benefits, including anti-aging, anti-inflammatory, and anti-oxidative properties. Antioxidants are widely used in the food industry to enhance the taste and safety of foods. Aromatic plants, such as thyme and Nigella sativa, contain phenolic compounds that have high antioxidant activity and can be used as natural alternatives to synthetic antioxidants in the food industry. Ergothioneine, a sulfur-containing compound, has excellent antioxidant effects and has potential applications in dermatology, cosmetics, and the food industry. Non-enzymatic antioxidants have been found to be more effective than enzymatic antioxidants in supporting embryonic development in vitro. Antioxidant supplementation, including polyphenols, CoQ10, Vitamin E, and N-acetylcysteine, has shown protective effects against noise-induced hearing loss in animal models and clinical trials.
What are the health benefits of antioxidants?5 answersAntioxidants have a variety of health benefits. They can protect cells from free radicals, which contribute to heart disease, cancer, and other diseases. Antioxidants also have anti-aging and anti-inflammatory properties. They enhance the taste and safety of a wide range of foods. Antioxidants have been shown to protect cells from oxidative damage in both lab settings and observational studies. They can reduce lipid peroxidation, detoxify free radicals, activate endogenous antioxidant enzymes, and reduce levels of pro-inflammatory cytokines. Natural antioxidants from fruits, plants, and other sources have different health-promoting effects. Exogenous antioxidants obtained from foods can work together with endogenous antioxidants to maintain the redox reaction balance in the body. Consuming a diet rich in antioxidants, particularly fruits and vegetables, is linked to superior overall health effects. In addition to diet, adopting an active lifestyle with consistent exercise and stress management is important for good health.

See what other people are reading

What factors contribute to the differences in healthcare delivery between traditional and modern methods in Thailand?
4 answers
The differences in healthcare delivery between traditional and modern methods in Thailand stem from various factors. Traditional Thai health practices, including Thai traditional medicine, pharmaceutics, midwifery, and massage, have reemerged as alternative and complementary approaches to Western medicine, emphasizing holistic care and self-reliance. In contrast, modern healthcare in Thailand, supported by policies like universal health coverage (UHC), focuses on providing essential services to all citizens, addressing changing disease profiles and an ageing population. Additionally, the country's emphasis on developing primary care systems aims to enhance UHC sustainability by prioritizing community-oriented, person-focused care within an integrated framework. These factors highlight the coexistence of traditional and modern healthcare approaches in Thailand, each with its unique strengths and contributions to the overall healthcare landscape.
What factors contribute to the differences in healthcare system between traditional and modern methods in Thailand?
5 answers
The differences in healthcare systems between traditional and modern methods in Thailand stem from various factors. Traditional Thai medicine (TTM) coexists with allopathic medicine, focusing on correcting imbalances of the four dhatu (earth, wind, water, and fire) through herbal medicines and therapies like Nuad Thai massage. While Western medicine gained prominence during modernization, traditional practices have resurged as holistic alternatives, emphasizing Thai traditional medicine, pharmaceutics, midwifery, and massage. Thailand's universal health coverage policy faces challenges due to disparities among health insurance schemes, aging population, and changing disease profiles, necessitating sustainable enhancements through prioritizing primary care for efficient and equitable healthcare access. Understanding these factors is crucial for bridging the gap between traditional and modern healthcare approaches in Thailand.
Does the Mediterranean diet help with breast cancer?
4 answers
The Mediterranean diet shows promising benefits in relation to breast cancer. Studies indicate that adherence to a Mediterranean-style diet is associated with a reduced risk of breast cancer. Specifically, findings suggest that high adherence to the Mediterranean diet is linked to lower odds of developing breast cancer, especially in postmenopausal women. Moreover, consuming a Mediterranean diet before a breast cancer diagnosis may improve long-term prognosis, particularly in postmenopausal women and cases of metastatic breast cancer. Additionally, research highlights an inverse association between high adherence to the Mediterranean diet and all-cause mortality among breast cancer survivors, emphasizing the potential of this dietary pattern to reduce the risk of mortality. These collective findings underscore the potential benefits of the Mediterranean diet in the context of breast cancer prevention and survivorship.
What is the optimal diet for human beings?
5 answers
The optimal diet for human beings is a whole food, high-fiber, low-fat, 90+% plant-based diet. This diet has been followed by humans throughout history and has shown to decrease mortality by 15%, decrease diabetes risk by 27%, and increase health benefits. Additionally, resorting to a whole-foods plant-based diet can prevent and even reverse chronic diseases like hypertension, hypercholesterolemia, coronary heart disease, vascular dementia, and diabetes. Observational studies and controlled trials support the idea that an evolutionary perspective is crucial in designing food models for optimal human health. Furthermore, a healthy diet not only influences cardiovascular risk but also has a significant impact on the environment, emphasizing the need for a transformation in the food system to decrease environmental impact.
Is there a difference between the field metabolic rate of birds and mammals?
5 answers
Yes, there is a difference between the field metabolic rates (FMR) of birds and mammals. Birds generally exhibit a higher FMR compared to mammals. The FMR of birds and mammals varies significantly based on body mass, with birds and mammals showing different scaling relationships between metabolic rate and body size. Birds consuming plant matter tend to have lower FMR compared to other dietary groups, while marine species and nectarivores exhibit higher FMR values. Additionally, the evolutionary age of the taxonomic group influences the metabolic rate, with younger groups having higher metabolic rates that increase more slowly with body weight. These findings highlight the diverse metabolic characteristics between birds and mammals, influenced by factors such as diet, habitat, and evolutionary history.
What is the muscle loss with age?
4 answers
Muscle loss with age, known as sarcopenia, is a significant component of the ageing process, impacting mortality, morbidity, frailty, and disability. Sarcopenia involves the unintentional decline in muscle mass and function as individuals age, leading to reduced force output and overall strength. Research has shown that sarcopenia is associated with various factors like inflammation, dysregulation of protein metabolism, and denervation, with a potential role of modified ROS generation and mitochondrial dysfunction. Additionally, studies have highlighted the impact of muscle loss on fluid volume maintenance and blood pressure regulation, potentially increasing the risk of orthostatic hypotension in older adults. Strategies targeting muscle loss in ageing, such as pharmacological stimulation of specific receptors like A2B, have shown promising results in restoring muscle function and combating age-related changes.
Is chronic inflammation a hallmark of aging?
5 answers
Chronic inflammation is indeed recognized as a hallmark of aging, referred to as "inflammaging" in the literature. This low-grade chronic inflammation, independent of overt infection, is associated with increased morbidity and mortality in the aging population. The dysregulation of inflammatory processes during aging disrupts the balance between pro-inflammatory and anti-inflammatory signaling, leading to a persistent inflammatory state that exacerbates the progression of aging and age-related diseases. Factors like the senescence-associated secretory phenotype (SASP) contribute to chronic inflammation, creating a vicious cycle with cellular senescence and organ damage, further emphasizing inflammation as a key factor in aging. Additionally, the accumulation of damage triggering a proinflammatory state in tissues is a central aspect of aging, implicating inflammation in various age-related chronic diseases and functional decline.
How do different diets affect quolity of life?
5 answers
Different diets have varying impacts on quality of life (QoL). Studies have shown that healthy dietary patterns, such as the Mediterranean diet and those rich in fruits and vegetables, are associated with better QoL in both physical and mental components. In contrast, unhealthy diets, like those high in sugars and low in dietary fibers, are linked to lower QoL scores. Additionally, following a well-balanced diet, particularly plant-based with fresh fruits, vegetables, seafood, and healthy spices, can significantly improve QoL in individuals with knee osteoarthritis. Furthermore, improvements in diet quality, especially adherence to healthy dietary patterns like the Mediterranean diet, are correlated with enhancements in health-related quality of life over time, with more pronounced benefits observed in women.
Who long does an onion seed germinate?
5 answers
Onion seeds typically exhibit a short lifespan, losing viability within 1-2 years. Factors affecting seed germination and vigor include seed moisture content, storage conditions, and seed treatments. Studies have shown that seed germination and vigor are highest at physiological maturity. Seed longevity can be determined through vigor tests like radicle emergence (RE test), which correlates with seed quality and viability over time. Additionally, the recovery of seed germination in aged onion seeds can be improved through chemical solutions like gibberellic acid and calcium chloride. Proper storage methods, such as maintaining low seed moisture levels and using appropriate packing materials like laminated aluminum bags with vacuum packing, can significantly extend the viability of onion seeds up to 27 months.
Does gut microbiome diversity decrease between adulthood and old age in mice?
5 answers
The gut microbiome diversity in mice tends to decrease between adulthood and old age. Studies have shown that aging is associated with alterations in the gut microbiota, leading to changes in microbial composition and function. In older mice, there is a reduction in alpha diversity, indicating a less diverse microbiome, compared to adult mice. Additionally, the longitudinal analysis of sibling mice revealed a significant diversification of the gut microbiome with age, showing a positive correlation between longevity and alpha diversity in middle age and a negative correlation in old age. Furthermore, the effect of oral bacteria like Porphyromonas gingivalis on the gut microbiome is more pronounced in old mice, leading to reduced diversity and abundance of beneficial bacteria. These findings collectively suggest a decrease in gut microbiome diversity from adulthood to old age in mice.
What factors influence the confidence of LGBTQ individuals in cross-dressing?
5 answers
The confidence of LGBTQ individuals in cross-dressing is influenced by various factors. Research indicates that self-esteem, interpersonal control, social confidence, and self-monitoring play significant roles. Factors such as perceived skill in cross-dressing, knowledge of cross-dressing, and acceptance of cross-dressing also impact confidence levels. Additionally, the societal stigma and fear of rejection experienced by LGBTQ individuals due to their sexual orientation contribute to a lack of confidence in expressing their identity openly. Moreover, affiliating with LGBTQ friends and family members, holding liberal political beliefs, and having less traditional gender role beliefs are associated with more positive attitudes and behaviors towards transgender individuals, which can potentially boost confidence in cross-dressing. These findings highlight the complex interplay of personal characteristics and societal influences on the confidence of LGBTQ individuals in cross-dressing.