How do you heal cannabinoid receptors?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
| This increased availability of endocannabinoids might stimulate cannabinoid receptors in a pathophysiological manner. | |
| However, new data, presented by Tam and colleagues in this issue of the JCI, demonstrate that selective blockade of peripheral cannabinoid receptors may be a novel successful therapeutic approach. | |
| The results indicate that modulating cannabinoid receptors represent a valuable approach for the treatment of neuropathic pain. | |
| These observations and others thus suggest that a natural function of cannabinoid receptors and their endogenous ligands is to regulate pain sensitivity. | |
40 Citations | These data demonstrate that neurite remodeling is a newly discovered function of CB1 cannabinoid receptors. |
| In particular, emerging evidence suggests that agonists of cannabinoid receptors expressed by tumor cells may offer a novel strategy to treat cancer. | |
20 Citations | However, emerging evidences suggest the role of cannabinoid receptors (CBRs) in curtailing the progression of PD by activating neuroprotective pathways. |
| Targeting the cannabinoid receptors has the potential to treat a variety of conditions such as pain, neurodegeneration, appetite, immune function, anxiety, cancer, and others. | |
| Cannabinoid receptors thus have the potential to prevent other Gi/o-coupled receptors from transducing their biological signals. | |
29 Citations | Our results provide further evidence that activation of peripheral cannabinoid receptors may be a useful target for the treatment of cancer pain. |
Related Questions
How to repair the endocannabinoid system?5 answersRepairing the endocannabinoid system involves enhancing the on-demand action of endocannabinoids to promote endogenous repair signaling. This can be achieved by modulating the availability of endocannabinoids through blocking their deactivation processes, such as inhibiting enzymes like fatty acid amide hydrolase and monoacylglycerol lipase. Additionally, incorporating butyrate-producing bacteria into the gut microbiota can help modulate the endocannabinoid system, potentially aiding in re-establishing metabolic homeostasis and alleviating metabolic syndrome. Furthermore, research suggests that targeting the endocannabinoid system could be advantageous for maintaining cartilage, bone, and synovium homeostasis to prevent the progression of osteoarthritis. Overall, these approaches highlight the potential strategies for repairing and optimizing the endocannabinoid system to promote neuroprotection and metabolic health.
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