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How long does it take for androgen receptors to recover? 

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The most likely mechanism for this loss of androgen sensitivity at higher testosterone concentrations is the finite capacity of the androgen receptor to bind androgen.
This method demonstrates that androgen receptors can withstand harsh denaturation conditions and should prove to be a valuable tool for purifying the human androgen receptor.
The decrease during recovery phase may be explained by a pharmacological down-regulation of the androgen receptors.
All cellular androgen receptors appear to be retained, because receptor content in sections was comparable to the sum of receptors in subcellular fractions of homogenized tissue.
Functional studies and immunoblot assays of the androgen receptors in patients with androgen resistance indicate that in most cases the phenotypic abnormalities are the result of impairment of receptor function or decreases in receptor abundance or both.
Our data indicate that the functional status of androgen receptors is strongly correlated with the phosphorylation status of the receptors, and that the phosphorylated androgen receptor is the form of the receptor transcriptionally active in regulation.
Preliminary findings suggest that androgen receptors are expressed during this time.
These results suggest that two states of transformed androgen receptors exist.
Furthermore, it is sensitive to relatively fast changes in the level of androgen receptors stimulation.
This androgen-sensitive pattern of misbehavior of the present mutant receptor distinguishes it from those responsible for 3 other families with partial androgen resistance studied previously.

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