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How long does it take for serotonin receptors to recover? 

Serotonergic
5-HT receptor
Receptor
Serotonin
Serotonin uptake

Answers from top 10 papers

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Papers (10)Insight
Journal Article•DOI
Functional evidence that chronic drugs induce adaptive changes of central autoreceptors regulating serotonin release.
Guido Maura, Maurizio Raiteri 
27 Jan 1984-European Journal of Pharmacology
28 Citations
The results indicate that, after long-term blockade or stimulation, serotonin autoreceptors become respectively hyper- or hyposensitive towards serotonin.
Journal Article•DOI
Neurotoxic effect of MDMA on brain serotonin neurons: evidence from neurochemical and radioligand binding studies.
Errol B. De Souza, George Battaglia, Thomas R. Insel 
01 Oct 1990-Annals of the New York Academy of Sciences
55 Citations
recovery of serotonin uptake sites) while functional recovery may be permanently impaired since serotonin content remains markedly (40-50%) below levels in age-matched controls for as long as one year after drug administration.
Open access•Journal Article•DOI
Internalization and recycling of 5-HT2A receptors activated by serotonin and protein kinase C-mediated mechanisms
Samarjit Bhattacharyya, Sapna Puri, Ricardo Miledi, Mitradas M. Panicker 
29 Oct 2002-Proceedings of the National Academy of Sciences of the United States of America
88 Citations
Our study suggests that 5-HT2A receptors internalize and return to the surface after both serotonin- and PKC-mediated processes.
Open access
Inhibition of serotonin reuptake.
R W Fuller, D T Wong 
01 Jul 1977
152 Citations
This decrease in serotonin turnover and release may be a compensatroy mechanism in response to an enhanced action of serotonin on synaptic receptors.
Book Chapter•DOI
Influence of Serotonin on the Blood–Brain and the Blood–Spinal Cord Barriers
Hari Shanker Sharma
01 Jan 2004
18 Citations
This effect of serotonin is mediated via serotonergic receptors.
Journal Article•DOI
Regional brain serotonin receptor changes in differentially housed mice: effects of amphetamine
E.J. Essman, Luigi Valzelli 
01 Apr 1984-Pharmacological Research Communications
11 Citations
The modified response, in isolated, aggressive mice, to several agents specific to serotonin receptors in the brain suggests an altered receptor availability for serotonin-like ligands.
Journal Article•DOI
In vitro and in vivo irreversible blockade of cortical S2 serotonin receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline: a technique for investigating S2 serotonin receptor recovery.
George Battaglia, Andrew B. Norman, Patricia L. Newton, Ian Creese 
01 Feb 1986-Journal of Neurochemistry
32 Citations
These data demonstrate that EEDQ in vitro and in vivo acts as an irreversible antagonist of S2 serotonin receptors and that it can be used to investigate the recovery rate of these receptors.
Journal Article•DOI
Multiple mechanisms of serotonin 5-HT2 receptor desensitization.
Shafiqur Rahman, Richard S. Neuman 
20 Jul 1993-European Journal of Pharmacology
42 Citations
We conclude that serotonin 5-HT2 receptors both induce and undergo several forms of desensitization.
Open access•Journal Article•DOI
Serotonin Promotes Development and Regeneration of Spinal Motor Neurons in Zebrafish.
Antón Barreiro-Iglesias, Karolina S. Mysiak, Angela L. M. Scott, Michell M. Reimer, Yujie Yang, Catherina G. Becker, Thomas Becker 
03 Nov 2015-Cell Reports
60 Citations
Pharmacological manipulations and receptor knockdown indicate that serotonin acts at least in part via 5-HT1A receptors.
Journal Article•DOI
Serotonin receptors in hippocampus and frontal cortex
Philip Seeman, Karen Westman, Donald V. Coscina, J.J. Warsch 
29 Aug 1980-European Journal of Pharmacology
88 Citations
These data support previous suggestions that supersensitivity develops specifically in serotonin receptors following afferent denervation.

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