How many strands of RNA does coronavirus have?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
61 Citations | Coronavirus have the largest RNA genomes (∼26–32 kilobases) and their expansion was likely enabled by acquiring enzyme functions that counter the commonly high error frequency of viral RNA polymerases. |
| Because coronavirus contains the longest viral RNA genome by far (and is probably one of the longest stable RNAs in nature), this approach seems to pave the way for the reverse genetics studies for all RNA viruses. | |
56 Citations | The data obtained in this study reveal a remarkable degree of structural and functional conservation of 5′-terminal RNA structural elements across coronavirus genus boundaries. |
| Six copies of a large coronavirus transmembrane protein formed the core of this structure, which may constitute a viral RNA export channel and provide a target for future antiviral interventions. | |
48 Citations | The data suggest that coronavirus replication involves an RNA superstructure at the 5′ end of the genome or one comprising both ends of the genomic RNA. |
Open access•Journal Article 48 Citations | Coronavirus RNA transcription and replication may serve as a paradigm of RNA synthesis for RNA viruses in general. |
| We find that highly stable RNA structures are pervasive throughout coronavirus genomes, and are conserved between the SARS-like CoV. | |
| Our data suggests that selective pressure helps preserve RNA secondary structure in coronavirus genomes, suggesting that these structures may play important roles in virus replication and pathogenesis. | |
53 Citations | This coronavirus can therefore be characterized as a positive-strand RNA virus. |
15 Citations | These findings suggest that coronavirus RNA synthesis is carried out on a ribonucleoprotein via a mechanism that involves both viral and cellular proteins associated with viral RNA, similar to DNA-dependent RNA transcription. |