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How many times we can use stem cells? 

Regenerative medicine
Adult stem cell
Stem cell
Clinical uses of mesenchymal stem cells
Cellular differentiation

Answers from top 12 papers

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Papers (12)Insight
Journal Article•DOI
Therapeutic window, a critical developmental stage for stem cell therapies.
Shengwen Calvin Li, Yuan-Ping Han, Brent A. Dethlefs, William G Loudon 
30 Nov 2010-Current Stem Cell Research & Therapy
16 Citations
Taken together, we can use selective processes to generate more effective stem cells to treat cancers as is clearly needed today.
Open access•Journal Article•DOI
Adipose-derived stem cell: a better stem cell than BMSC
Yanxia Zhu, Tian-Qing Liu, Kedong Song, Xiubo Fan, Xuehu Ma, Zhanfeng Cui 
01 Aug 2008-Cell Biochemistry and Function
547 Citations
In order to obtain more stem cells, we can subculture ADSCs every 14 days instead of the normal 5 days.
Open access•Journal Article•DOI
The effect of age on stem cell function and utility for therapy.
Patrick Narbonne
08 Jun 2018-Cell medicine
The use of stem cells from young donors or the rejuvenation of aged patient-derived stem cells may represent part of a solution.
Open access•Journal Article•DOI
Introduction to stem cells and regenerative medicine.
George Kolios, Yuben Moodley 
01 Jan 2013-Respiration
298 Citations
Stem cells can be used in cellular therapy to replace damaged cells or to regenerate organs.
Open access•Journal Article•DOI
Stem cell therapy for the heart.
Loren E. Wold, Wangde Dai, Casilde Sesti, Sharon L. Hale, Joan Dow, Bradley J. Martin, Robert A. Kloner 
01 Nov 2004-Congestive Heart Failure
16 Citations
Once these questions have been addressed, the use of stem cells in clinical practice can be realized.
Open access•Journal Article
Adult stem cells and their importance in cell therapy.
Stanislav Filip, J Mokrý, I Hruska 
01 Jan 2003-Folia Biologica
19 Citations
For their unique properties stem cells promise to be of universal use in clinical medicine, especially in regeneration of many organs and tissues in the human body.
Open access•Journal Article•DOI
Scaling-Up of Dental Pulp Stem Cells Isolated from Multiple Niches
Nelson F. Lizier, Alexandre Kerkis, Cícera M. Gomes, Josimeri Hebling, C.F. Oliveira, Arnold I. Caplan, Irina Kerkis 
29 Jun 2012-PLOS ONE
118 Citations
Substantial quantities of stem cells of an excellent quality and at early (2–5) passages are necessary for clinical use, which currently is a problem for use of adult stem cells.
Open access•Journal Article•DOI
Congress debates stem cell research.
Kristine Novak
01 Jun 2000-Nature Medicine
Fischbach added that unlike pluripotent stem cells, adult stem cells may be only capable of dividing a limited number of times, which would limit their therapeutic usefulness.
Open access•Journal Article
Role of stem cells in treatment of neurological disorder.
Ashfaq Ul Hassan, Ghulam Hassan, Zahida Rasool 
01 Jul 2009-International journal of health sciences
34 Citations
Unlike muscle cells, blood cells, or nerve cells -- which do not normally replicate themselves - stem cells may replicate many times.
Open access•Journal Article•DOI
Cancer stem cells persist in many cancer cell lines.
Takao Setoguchi, Tetsuya Taga, Toru Kondo 
02 Feb 2004-Cell Cycle
165 Citations
We propose that many cancer cell lines contain a minor subpopulation of stem cells that is enriched in a SP, can be maintained indefinitely in culture, and is crucial for their malignancy.
Open access•Journal Article•DOI
Stem cells in tissues, organoids, and cancers.
Xusheng Wang
17 Jul 2019-Cellular and Molecular Life Sciences
41 Citations
Nevertheless, in addition to the achievements in stem cell research, many challenges still need to be overcome for stem cells to have versatile application in clinics.
Open access•Journal Article•DOI
Adult stem cells: hopes and hypes of regenerative medicine.
Jozef Dulak, Krzysztof Szade, Agata Szade, Witold Nowak, Alicja Jozkowicz 
22 Jul 2015-Acta Biochimica Polonica
113 Citations
Therefore, the use of adult stem cells, which are multipotent or unipotent, can be at present a more achievable strategy.

Related Questions

How to use stem cell for cancer therapy?5 answersStem cells have emerged as a promising tool in cancer therapy due to their unique abilities. Cancer stem cells (CSCs) are crucial for tumor initiation, progression, and metastasis, making them a target for therapy. Studies focus on various stem cell types like mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) for their tumor-homing properties and anti-cancer effects. The "stemness" properties of CSCs, including self-renewal and differentiation capacity, contribute to therapy resistance and cancer relapse, highlighting the importance of targeting CSCs in treatment. Stem cells can be utilized to deliver drugs to tumor sites, enhance survival rates, and reduce tumor volume, showing promise in pre-clinical trials. Overall, utilizing stem cells in cancer therapy involves leveraging their unique characteristics to target and treat cancer effectively.
What ethical issues are associated with the use of stem cells?4 answersThe ethical issues associated with the use of stem cells include concerns about the source of human embryonic stem cells and the derivation and use of other stem cells that have the capacity to differentiate into all types of human tissue. There are also ethical considerations regarding the use of induced pluripotent stem cells (iPSCs), which have the potential to avoid the destruction of human embryos. Additionally, there are ethical challenges related to the use of stem cells in clinical research and the translation of basic stem cell knowledge into safe and effective patient therapies. The procurement and use of pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, also raise ethical considerations. These ethical issues need to be addressed in order to ensure the responsible and ethical use of stem cells in research and clinical applications.
What are the practical uses of stem cells?5 answersStem cells have practical uses in various medical fields, including cellular therapy, regenerative medicine, and the treatment of neurological diseases. They can be used to replace damaged cells and tissues, aiding in the regeneration and repair of organs. Stem cell therapy shows potential in treating diseases such as leukemia, lymphoma, neuroblastoma, multiple myeloma, spinal cord injuries, diabetes, Parkinson's disease, Alzheimer's disease, heart disease, stroke, burns, cancer, and osteoarthritis. Additionally, stem cells have the ability to stop immune responses, making them useful in diseases where organs are damaged or the immune system is overactive. Pluripotent stem cells, in particular, have the potential to differentiate into all adult cell types, making them valuable in disease modeling and regenerative medicine. Genome editing tools like CRISPR Cas9 can be used to manipulate stem cells for studying and treating human diseases.
Are stem cells widely available?7 answers
Can you use stem cells to get smarter?10 answers
How many lives have been saved by stem cell research?10 answers

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