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How much does RNA seq Cost per sample? 

RNA
DNA microarray
RNA-Seq
Genomics
Reference genome

Answers from top 10 papers

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Papers (10)Insight
Open access•Journal Article•DOI
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li, Colin N. Dewey 
04 Aug 2011-BMC Bioinformatics
14.5K Citations
In addition, RSEM has enabled valuable guidance for cost-efficient design of quantification experiments with RNA-Seq, which is currently relatively expensive.
Open access•Journal Article•DOI
TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experiments.
Luisa F Pallares, Serge Picard, Julien F. Ayroles 
01 Jan 2020-G3: Genes, Genomes, Genetics
26 Citations
In contrast, RNA-seq protocols where each sample is processed individually are significantly more expensive and lower throughput than single-cell approaches.
Open access•Journal Article•DOI
A comparison of methods for differential expression analysis of RNA-seq data
Charlotte Soneson, Mauro Delorenzi, Mauro Delorenzi 
09 Mar 2013-BMC Bioinformatics
838 Citations
As the cost of sequencing decreases, it is conceivable that the use of RNA-seq for differential expression analysis will increase rapidly.
Open access•Journal Article•DOI
Transcriptomic Analysis of Petunia hybrida in Response to Salt Stress Using High Throughput RNA Sequencing
Gonzalo H. Villarino, Aureliano Bombarely, James J. Giovannoni, Michael J. Scanlon, Neil S. Mattson 
10 Apr 2014-PLOS ONE
45 Citations
The methodological improvement presented here could substantially reduce the cost of sample preparation for future high-throughput RNA sequencing experiments.
Book Chapter•DOI
Analysis of RNA Sequencing Data Using CLC Genomics Workbench.
Chia-Hsin Liu, Y. Peter Di 
01 Jan 2020-Methods of Molecular Biology
38 Citations
In addition, the increasing publicly available sequencing datasets and decreasing sequencing cost promote the use of RNA-seq for hypothesis-generating studies.
Open access•Journal Article•DOI
Systematic evaluation of RNA-Seq preparation protocol performance
Hsueh Ping Chao, Yueping Chen, Yoko Takata, Mary W. Tomida, Kevin Lin, Jason Kirk, Melissa S. Simper, Carol D. Mikulec, Joyce E. Rundhaug, Susan M. Fischer, Taiping Chen, Dean G. Tang, Dean G. Tang, Yue Lu, Jianjun Shen 
11 Jul 2019-BMC Genomics
28 Citations
Consequently, it is a pivotal parameter to consider when designing an RNA-Seq experiment.
Open access•Journal Article•DOI
Statistical Modeling of RNA-Seq Data
Julia Salzman, Hui Jiang, Wing Hung Wong 
01 Feb 2011-Statistical Science
98 Citations
By obtaining tens or even hundreds of millions of reads of transcribed sequences, an RNA-Seq experiment can offer a comprehensive survey of the population of genes (transcripts) in any sample of interest.
Open access•Journal Article•DOI
Simulation-based benchmarking of isoform quantification in single-cell RNA-seq
Jennifer Westoby, Marcela Sjöberg Herrera, Anne C. Ferguson-Smith, Martin Hemberg 
07 Nov 2018-Genome Biology
23 Citations
The reduction in performance compared with bulk RNA-seq is small.
Book Chapter•DOI
A rapid, simple, and inexpensive method for the preparation of strand-specific RNA-Seq libraries.
Arthur G. Hunt
01 Jan 2015-Methods of Molecular Biology
31 Citations
This report presents a simple, rapid, and inexpensive method for preparing strand-specific RNA-Seq libraries from varying quantities of total RNA.
Open access•Journal Article•DOI
RNA-seq differential expression studies: more sequence or more replication?
Yuwen Liu, Jie Zhou, Kevin P. White 
01 Feb 2014-Bioinformatics
443 Citations
We also propose a cost-effectiveness metric for guiding the design of large-scale RNA-seq DE studies.

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