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How much time does cell cycle of yeast takes? 

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Here we show that in budding yeast, the ability of cells to grow changes during the cell cycle.
2 h. Thus the cell cycle of yeast can be divided into an expandable phase from cell division to the initiation of DNA synthesis, the length of which is dependent on growth rate and a constant phase from the initiation of DNA synthesis to cell division which takes a constant time independent of generation time.
These findings underscore and extend earlier conclusions that most of the G1 interval of the yeast cell cycle is simply a period of ongoing growth.
These observations are predicted if a yeast cell requires a critical size before a particular cell cycle event can be completed and that after completion of this event cell division occurs following a period of time independent of growth rate.
We conclude that the yeast metabolic cycle is an intrinsic property of yeast metabolism and does not depend on either synchronization or external limitation of growth by the carbon source.
The characteristics and the time course of the yeast cell cycle were found to be strongly dependent on the physiological environment.
These results reveal the logic of cellular metabolism during different phases of the life of a yeast cell.
These data reveal fundamental scaling relationships between the duration of eukaryotic cell cycle phases and rates of cell proliferation, point to the necessary role of Cln3p in these relationships in yeast, and provide a mechanistic basis linking Cln3p levels to proliferation rates and the scaling of G1 with doubling time.
Open accessJournal ArticleDOI
Xiaoyan Leng, Hans-Georg Müller 
01 Oct 2006-Biostatistics
34 Citations
The application to yeast cell-cycle data establishes a natural time order of genes that is in line with cell-cycle phases.
Here we present evidence for an independent cell-cycle oscillator in the budding yeast Saccharomyces cerevisiae.

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How is cell cycle regulation important in yeast?5 answersCell cycle regulation is important in yeast because it plays a crucial role in coordinating metabolism, growth, and cell division. The regulatory mechanisms driving cell cycle progression involve an interacting network of transcription factors, cyclin-dependent kinases, and ubiquitin ligases. This network must produce robust periodic behavior during proliferative phases and have the ability to halt the cycle when unfavorable conditions trigger a checkpoint arrest. The cell cycle also regulates metabolism, as evidenced by extensive cell cycle-dependent phosphorylation and dephosphorylation of metabolic enzymes. This regulation is achieved through protein phosphorylation, with CDK consensus motifs and arginine-directed motifs being highly enriched. The coordination of cell cycle and metabolism is essential for temporally coordinating biosynthesis with distinct phases of the cell division cycle.
What is the size of yeasts?5 answersYeasts are unicellular fungal cells with a diameter of about 3-5 µm. They are larger than bacteria, which have dimensions of 0.5 × 5 μm. Yeast cells are generally about 5 to 10 microns in diameter.
How does the histone coverage of DNA change in yeast chronological ageing?4 answersHistone coverage of DNA changes during yeast chronological aging. Reduction in histone protein levels occurs, leading to a decrease in nucleosome occupancy across the genome. Nucleosomes become less well positioned or move to sequences that better accommodate histone octamers. The loss of histones during aging results in the transcriptional induction of all yeast genes, with genes normally repressed by promoter nucleosomes being most induced. Additionally, the altered chromatin dynamics in yeast cells without the linker histone Hho1p lead to strong alterations in the gene expression profiles of genes involved in DNA repair and autophagy. The interaction between Hho1p and Arp4p is crucial for maintaining chromatin organization during chronological aging. The importance of a healthy interaction between Arp4p and Hho1p in replicative aging is also significant. The results suggest that higher-order chromatin structures and interactions among chromatin proteins play a crucial role in maintaining chromatin organization during chronological aging.
How long does it take DNA replication to occur?5 answers

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