How much time does cell cycle of yeast takes?
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Here we show that in budding yeast, the ability of cells to grow changes during the cell cycle. | |
38 Citations | 2 h. Thus the cell cycle of yeast can be divided into an expandable phase from cell division to the initiation of DNA synthesis, the length of which is dependent on growth rate and a constant phase from the initiation of DNA synthesis to cell division which takes a constant time independent of generation time. |
These findings underscore and extend earlier conclusions that most of the G1 interval of the yeast cell cycle is simply a period of ongoing growth. | |
68 Citations | These observations are predicted if a yeast cell requires a critical size before a particular cell cycle event can be completed and that after completion of this event cell division occurs following a period of time independent of growth rate. |
We conclude that the yeast metabolic cycle is an intrinsic property of yeast metabolism and does not depend on either synchronization or external limitation of growth by the carbon source. | |
100 Citations | The characteristics and the time course of the yeast cell cycle were found to be strongly dependent on the physiological environment. |
These results reveal the logic of cellular metabolism during different phases of the life of a yeast cell. | |
These data reveal fundamental scaling relationships between the duration of eukaryotic cell cycle phases and rates of cell proliferation, point to the necessary role of Cln3p in these relationships in yeast, and provide a mechanistic basis linking Cln3p levels to proliferation rates and the scaling of G1 with doubling time. | |
The application to yeast cell-cycle data establishes a natural time order of genes that is in line with cell-cycle phases. | |
119 Citations | Here we present evidence for an independent cell-cycle oscillator in the budding yeast Saccharomyces cerevisiae. |
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