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How much time does it take for mutation in West Bengal? 

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Book ChapterDOI
41 Citations
It may take a very long time before the mutation manifests because a number of other quite improbable events must also take place.
For it seems possible that the intensity of natural radiation produces a minimum mutation rate per unit of time which is often exceeded (as in Drosophila) but below
Genotyping indicates that long latency P. vivax is prevalent in West Bengal, and that the first relapses after long latent periods are genetically homologous.
The geographic gradient in the frequency of the mutation, along with findings on polymorphic haplotype distribution, suggest that the mutation is relatively young in evolutionary terms and spread as the result of west and south‐bound migrations originating from Georgia.
This suggests a low per unit time mutation rate as the generation time is much longer in peach.
The mutation does not seem to be common in populations other than Ashkenazi Jews, where it is found at a …
The mutation rate would evolve in response to the risk of runaway mutation, in particular, when the generation time changes.
The distribution of ailments suggest that West Bengal is passing through the advanced phase of epidemiologic transition in which communicable diseases are being swiftly replaced with rising levels of non-communicable diseases.
Mass awareness, education and genetic counselling are required to prevent the spread of this mutation among this tribal population of West Bengal.
Open accessJournal ArticleDOI
John D.H. Stead, Alec J. Jeffreys 
22 Mar 2000
57 Citations
Its bimodal allele size distribution in Caucasians suggests a much lower mutation rate and possible differences in the mutation process compared with highly unstable minisatellites.

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