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The incubation of platelets with GSNO improved the percentage aggregation and abolished the latency time.
C. papaya L. leaf extracts showed a significant inhibition of hemolysis in vitro and could have a potential therapeutic effect on disease processes causing destabilization of biological membranes.
This biotechnological approach could be adopted to enhance papaya-juice production by local fruit juice processors when parameters for scale-up processes are established.
The juice of papaya leaves is the best option for increasing the platelet count.
Studies have indicated that the juice of the leaves of the Carica papaya plant from the family Caricaceae could help to increase the platelet levels in these patients.
In general, the consumption of apples or apple juice as well as oranges, grapefruit and cruciferous vegetables, sources of large amounts of tested derivatives, have beneficial effects on platelets under oxidative stress.
C. papaya leaf extract can be considered as a potential candidate for increase in platelet count in patients of dengue, however; there is need of high-quality evidence in the form of large clinical trials before a decision related to the use of such extract is made.
Suggestively, C. papaya extracts could be used to enhance the production of selected blood parameters, taking issue of dosage into consideration.
The supplements of C. papaya leaves have shown promising prospect due to the platelet increasing property.
This suggests consumption of large platelets at time of thrombus formation.

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