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This process is probably independent of the zinc concentration.
The results of the present experiment indicate that the zinc tolerance test, that is, an unequivocal rise in serum zinc following per oral administration of this metal, provides the best indication of zinc status.
A zinc tolerance determination of this kind may be of value in differentiating clinical entities in which zinc deficiency may occur.
Leucocyte zinc therefore appears to have a limited value in the assessment of marginally impaired zinc status, except in inflammatory states.
The model is able to explain the experimental evidence collected so far in our laboratory: high zinc yields are only obtained if the zinc/oxygen mixture is strongly diluted with inert gas.
The authors present a new model of zinc currents and zinc toxicity that offers expanded opportunities for zinc-selective therapeutic chelation interventions.
The kinetic analysis with a compartmental model suggests that the profound decrease in plasma zinc concentrations after 5 wk of severe zinc depletion was mainly due to a decrease in the rate of zinc release from the most slowly turning over body zinc pool.
Open accessJournal ArticleDOI
Sat Parkash, Robert Jenness 
34 Citations
The solubilization of bound zinc by adding graded amounts of EDTA to skimmilk further supports the conclusion that zinc is bound in two different manners.

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