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How protein composition change during spermatogenesis? 


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During spermatogenesis, there are significant changes in protein composition. Proteasome complexes play a crucial role in this process, with the spermatoproteasome (s20S) being specific to developing gametes. The s20S becomes highly activated during meiosis, mainly through association with proteasome activators PA200 and 19S. The population of proteasomes shifts from predominantly constitutive proteasomes (c20S) to predominantly s20S during differentiation, likely due to the shift in expression of the α4 subunit to α4s. The s20S interacts with components of the synaptonemal complex, which connects homologous chromosomes during meiosis. In vitro, the s20S displays higher trypsin- and chymotrypsin-like activities, both with and without PA200 activation. Differences in domain flexibility between α4 and α4s induce changes in the way the s20S interacts with its partners, dictating its role in germ cell differentiation .

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The paper discusses the changes in protein composition during spermatogenesis, specifically focusing on the proteasome subtype called s20S and its interaction with various proteins and complexes involved in germ cell development. However, it does not provide a detailed analysis of the overall protein composition changes during spermatogenesis.
The paper provides information on the transition of basic protein during spermatogenesis in Fenneropenaeus chinensis, but it does not specifically mention how the protein composition changes during spermatogenesis.
The paper discusses the changes in protein composition during spermatogenesis, specifically focusing on the proteasome complexes. It describes how the s20S proteasome subtype becomes highly activated during meiosis and undergoes a shift in population from c20S to s20S. The paper also mentions the interaction of s20S with components of the meiotic synaptonemal complex. However, it does not provide a comprehensive analysis of the overall protein composition changes during spermatogenesis.
The paper discusses the extensive structural and functional reorganization of chromatin during spermatogenesis, including the expression of testis-specific histone variants and other chromatin proteins. However, it does not specifically mention how the protein composition changes during spermatogenesis.
The protein composition changes during spermatogenesis as the proteasome population shifts from c20S to s20S, and the s20S becomes highly activated during meiosis.

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