How to calculate percentage drug release in Excel?
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138 Citations | We showed that this model was able to predict the resulting drug release kinetics accurately in all cases. |
| In this paper, a mathematical model is proposed to find the suitable values of the controllable factors in a drug to achieve the profile of the drug release in the patient’s body. The proposed method has several advantages over the existing methods. The authors feel that by adjusting the control factors during the production process the drug release profile become closer to the reference profile. | |
| Mathematical treatment of the in vitro drug release data suggests that, all the formulations best fitted into first order release kinetics. | |
17 Citations | The results obtained permit us to conclude that the division, in this case, affects the drug release characteristics. |
38 Citations | The models give excellent reproduction of drug release profiles within the whole release period, and the parameters can be correlated to various factors such as γ-irradiation dose, copolymer composition, and initial drug loading, this correlation indicates that the new models can be used to predict the effects of various factors on drug release profiles based on limited experimental data. |
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Can you show me step by step calculations for drug release for this paper https://www.sciencedirect.com/science/article/pii/S0378517316302320?5 answersStep 1: The drug release process can be simulated using a phase-field model, which accurately predicts the release profile and can be applied to different materials. Another study presents a method for predicting drug-release profiles based on physical mechanisms, incorporating the effects of drug concentration and flow rates. Additionally, a multi-layer diffusion model is proposed for estimating the release time of drug-filled capsules, providing useful indicators without explicit calculation of the full transient solution. Furthermore, a paper discusses the fabrication of thermosensitive and magnetic response drug release systems, highlighting their step-by-step release behaviors and environmental responsiveness. Both approaches provide computationally-cheap and useful tools for quantifying the release time of different composite microcapsule configurations.
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Context_1: Li et al.
Context_2: Abbasnezhad et al.
Context_3: Carr and Pontrelli
Context_4: Lv et al.
Context_5: Carr and Pontrelli
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The drug release process can be simulated using a phase-field model, which accurately predicts the release profile and can be applied to different materials. Another study presents a method for predicting drug-release profiles based on physical mechanisms, incorporating the effects of drug concentration and flow rates. Additionally, a multi-layer diffusion model is proposed for estimating the release time of drug-filled capsules, providing useful indicators without explicit calculation of the full transient solution. Furthermore, a paper discusses the fabrication of thermosensitive and magnetic response drug release systems, highlighting their step-by-step release behaviors and environmental responsiveness. Both approaches provide computationally-cheap and useful tools for quantifying the release time of different composite microcapsule configurations.
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