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How to increase estrogen to increase breast? 

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Interestingly, these factors converge to increase aromatase expression within the breast and hence, estrogen production, thereby increasing the risk of breast cancer and the growth of breast tumour cells.
These studies may provide not only new clues for elucidation of the molecular mechanisms of estrogen-dependent growth of breast cancer, but also assessment of anti-estrogen responses of individual breast cancer for patient-tailored hormone therapy.
An increase in breast density is significantly more frequent in women receiving combined estrogen-progestin therapy than in women receiving estrogen alone.
Inhibition of aromatase to reduce estrogen production by peripheral and ovarian tissue could be a useful approach to treating hormone-dependent breast cancer.
Inhibition of estrogen synthesis by selective blockade of the aromatase enzyme could be an effective systemic means of reducing estrogen production and treating patients with breast cancer.
This increase appears to be prevented by estrogen-replacement therapy.
Therefore, the conflicting results regarding the effects of phytoestrogens on breast cells may be attributed to the endogenous estrogen present in breast tissue.
About one in five women experienced an increase in breast size after menopause.
Estrogen induction of free extracellular VEGF may be one mechanism involved in sex steroid–dependent breast carcinogenesis.
A study to differentiate the microenvironmental regulation of estrogen-dependent and -independent breast cancer growth would also be useful to improve hormone therapy for breast cancer.
Our study suggests that hormone replacement therapy may suspend breast involution but does not increase breast density in the majority of patients.
Growth factors may act as estrogen-induced "second messengers" in estrogen-responsive growth of human breast cancer.
Our data suggest that estrogen may be involved in the regulation of aromatase activity in breast tissues.
This adaptation may have important physiological and nutritional significance on estrogen dependent growth of breast tumors.
Journal ArticleDOI
W.R. Miller, J. O'Neill 
01 Oct 1987-Steroids
282 Citations
These results emphasize the importance of local estrogen synthesis within the breast in terms of both the natural history and behavior of breast cancers.

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