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How to increase macrophage activity?

Pyruvate dehydrogenase kinase

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Open access•Journal Article•DOI PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages. Annemarie Guentsch, Angelika Beneke, Lija Swain, Katja Farhat, Shunmugam Nagarajan, Ben Wielockx, Kaamini Raithatha, Jan Dudek, Peter Rehling, Anke Zieseniss, Aline Jatho, Mei Chong, Celio X.C. Santos, Ajay M. Shah, Dörthe M. Katschinski - Show less +14 more 01 Jan 2017-Molecular and Cellular Biology 27 Citations	We suggest that PHD2 serves as an adjustable switch to control macrophage behavior.
Journal Article•DOI Phagocytosis, endosomal/lysosomal system and other cellularaspects of macrophage activation by Canova medication Luciana Lopes, Lyris M.F. Godoy, Carolina Camargo de Oliveira, Juarez Gabardo, Ruth Janice Guse Schadeck, Dorly de Freitas Buchi - Show less +5 more 01 Apr 2006-Micron 42 Citations	The net results demonstrate that Canova medication is an effective stimulator of macrophage activity.
Journal Article•DOI AN Improved Macrophage Spreading Assay - A Simple and Effective Measure of Activation Ken Donaldson, R E Bolton, David M. Brown, A. Douglas - Show less +3 more 01 Jan 1984 24 Citations	The macrophage spreading assay described here is quick, reliable, consistent and easy to perform and has a potentially wide application in studies of macrophage function and dysfunction.
Open access•Journal Article•DOI Immunobiology of the Macrophage A. J. S. Davies 01 Jul 1977-Journal of Clinical Pathology 43 Citations	This immunobiology of the macrophage can help you to solve the problem.

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What is the role of macrophage stimulate colony factor?4 answersMacrophage colony-stimulating factor (CSF1) is a cytokine that plays a crucial role in the control of monocyte and macrophage differentiation, survival, proliferation, and renewal. It is widely expressed and primarily produced by cells of mesenchymal lineages. CSF1 has been shown to contribute to the maintenance of tissue-specific macrophage populations. Administration of recombinant CSF1 leads to monocytosis, expansion of tissue macrophage populations, and growth of the liver and spleen. In various tissue injury models, CSF1 promotes monocyte infiltration, clearance of damaged cells, and repair. Additionally, CSF1 has been implicated in the pathology of diseases such as atherosclerosis, lupus nephritis, and multiple sclerosis (MS). In the context of MS, GM-CSF, a subtype of CSF1, has been found to play a critical role in mediating MS pathology and is being targeted in clinical trials. Overall, CSF1 is a key regulator of macrophage function and has implications in various diseases.

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