Is 20 hours enough for autophagy?
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Instead, effect size analyses suggest a modest-to-large increase in autophagy flux following exercise that lasts up to 24 hours. | |
2.2K Citations | Our results suggest that the regulation of autophagy is organ dependent and the role of autophagy is not restricted to the starvation response. |
409 Citations | Regulation of the capacity of the core autophagy machinery also affects selective autophagy. |
Daniel J. Klionsky +2983 more 1.1K Citations | Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. |
A broad understanding of autophagy, ranging from detailed processes, including induction, formation and degradation, to function in physiology and pathology, revealed by accumulating studies, may be helpful for formulating therapeutic strategies for autophagy-associated human diseases. | |
Daniel J. Klionsky +2983 more 1.1K Citations | Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. |
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