Is anastrozole an immunotherapy drug?
Answers from top 14 papers
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| Papers (14) | Insight |
|---|---|
14 Citations | This study is the first to investigate treatment with fulvestrant 500 mg combined with anastrozole. |
| is more effective compared with anastrozole (1.0 mg o. d.) | |
| In conclusion, provided that a sufficient time horizon is taken and that long-term model predictions are confirmed from further follow-up from the ATAC study, anastrozole is a highly cost-effective adjuvant therapy compared to tamoxifen. | |
| Fulvestrant was as effective as anastrozole. | |
564 Citations | In postmenopausal women with hormonally sensitive ABC, anastrozole should be considered as the new standard first-line treatment. |
| The higher 10 mg dose did not result in additional clinical benefit, but was well tolerated reflecting the good therapeutic margin with anastrozole. | |
11 Citations | Finally, anastrozole substantially reduces the incidence of contralateral breast cancer compared with tamoxifen in women with HR+ early breast cancer and, therefore, is a potential chemopreventive agent. |
11 Citations | Anastrozole is thus positioned to become the standard care for postmenopausal women with HR+ disease across the whole breast cancer continuum. |
11 Citations | In advanced disease, anastrozole has a significant survival benefit and tolerability advantage compared with megestrol acetate when used as second-line treatment. |
11 Citations | In the adjuvant setting, anastrozole has superior efficacy and tolerability compared with tamoxifen in newly diagnosed patients and those who have already received 2–3 years’ prior adjuvant tamoxifen. |
| These findings represent potential steps towards individualized anastrozole therapy. | |
11 Citations | Furthermore, anastrozole has preoperative efficacy in HR+ large or locally advanced tumors. |
| The use of anastrozole was associated with a higher incidence of CTS but few participants required surgery. | |
| RESULT(S) The pharmacokinetics of anastrozole were linear, predictable, and consistent with previously published data in healthy volunteers. |