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Although increasing evidence shows that ATL-I has an anti-inflammatory effect, the anti-inflammatory molecular mechanism of ATL-I is still unknown.
atRA shows promise by acting in a directly anti-inflammatory manner, whereas further research into the exact mechanisms and behaviours of hMSCs in inflammatory diseases is required.
Our study provides scientific evidence to support the traditional anti-inflammatory uses of Atropa acuminata and is probably due to inhibitory effects on multiple inflammatory mediators which indicates a promising potential for the development of a strong anti-inflammatory agent from this plant.
It is likely that oxidative stress and inflammatory mediators contributed to the pathogenesis of NEC and that ATRA had a protective effect on intestinal injury through its anti-inflammatory and antioxidant properties.
It is, therefore, endowed with anti-inflammatory properties.
Open accessJournal ArticleDOI
G Kafeel, P U Telesinghe 
54 Citations
The lesion is clearly inflammatory and reactive, but the aetiology remains unknown.
Hence the anti-inflammatory effect of PPARalpha overrides the pro-inflammatory effect of AhR.
The signaling attenuates inflammatory activity.
Discussion and conclusion: C. athoa is suggested to be a potential source of lead compounds for inflammatory diseases due to the significant in vitro and in vivo anti-inflammatory results.

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