Is Hepatitis a risk factor for oral cancer?
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| Oral hygiene also may confound the association of nutrition and oral cancer risk; it is likely to be associated with dietary practice, and it has been shown to be related to oral cancer risk. | |
33 Citations | In addition, subjects with HCV infection tend to be at early onset risk for oral cavity cancer. |
| These findings indicate that oral hygiene and several oral conditions are risk factors for oral cancer, independently of the known risks associated with smoking and drinking. | |
77 Citations | Subgroup analyses showed that low SES was significantly associated with increased oral cancer risk in high- and lower-income countries, across the world, and remained when adjusting for potential behavioural confounders. Oral cancer risk associated with low SES is significant and related to lifestyle risk factors. |
16 Citations | The smoking factor may have a commonality linking oral health with an increased risk for malignant disease. |
33 Citations | Our data suggest that HCV but not HBV infection is a risk factor for oral cavity cancer. |
| According to dental students, dentists should discuss HPV as a risk factor for oral cancer with patients. | |
60 Citations | These results suggest that alcohol concentration is a risk factor for oral cancer independent of the total quantity of alcohol consumed. |
| In addition, there is a significant increased risk for oral cancer among lower socioeconomic groups, males and older age groups. | |
170 Citations | In conclusion, the most important risk factor for developing oral cancer is tobacco consumption followed by alcohol consumption. |
Related Questions
What papers show the relationship between SSI and oral cancer surgery?4 answersThe relationship between Surgical Site Infections (SSI) and oral cancer surgery has been extensively studied in various research papers. Balagopal et al. found that SSIs were noticed in 8% of post-operative cases in oral cancer surgery, with a microbial spectrum predominantly consisting of gram-negative bacterial isolates. Hiraoka et al. identified preoperative nutritional indicators and platelet/lymphocyte ratio as independent prognostic factors affecting survival and SSI risk in oral cancer patients after reconstructive surgery. Additionally, Lin et al. highlighted the significance of the systemic inflammation response index (SIRI) in predicting the prognosis of postoperative oral squamous cell carcinoma patients, with higher SIRI levels correlating with increased mortality risk. These studies collectively emphasize the importance of infection prevention strategies and preoperative nutritional interventions in improving outcomes for patients undergoing oral cancer surgery.
What are the most common risk factors associated with oral cancer?5 answersThe most common risk factors associated with oral cancer include tobacco use, alcohol consumption, poor oral health, HPV infection, and betel quid chewing. Tobacco and alcohol are identified as the strongest risk factors for oral cancer, especially in low and middle-income countries. Additionally, poor oral health, such as periodontal disease, poor oral hygiene, and tooth loss, significantly increase the risk of developing oral cancer. HPV infection, particularly HPV16, is also a significant risk factor, especially when combined with smoking and alcohol consumption, leading to a strong interaction that elevates the risk of oral cancer, particularly oropharyngeal cancer. Betel quid chewing is another established risk factor, especially in Southeast Asian countries. Gender and lifestyle factors can also influence the clinical presentation of oral cancer, with smoking and alcohol abuse being common risk factors.
What is oral cancer epidemiology worildwide?5 answersOral cancer has a significant global burden, with variations in incidence and prevalence across different regions. The highest incidence rates are found in India, the United States, China, Pakistan, and Bangladesh. The disease is more common in males and the risk increases with age. Risk factors for oral cancer include tobacco smoke, alcohol drinking, viral infections, exposure to sunlight, and socioeconomic status. The World Health Organization's GLOBOCAN project highlights the high incidence and mortality rates in males, which is consistent with trends observed in America and Chile. Focused public health measures are needed to reduce the incidence and mortality of oral cancer worldwide. Strategies for prevention include tobacco and alcohol control, vaccination against HPV infection, early detection through screening, and risk reduction through training programs for physicians and patients.
What is the association between hepatitis C and salivary gland tumors?4 answersHepatitis C virus (HCV) infection has been associated with various extrahepatic manifestations (EHM), including salivary gland disorders. HCV-infected patients may exhibit histological signs of Sjogren-like sialadenitis, although the pathogenetic role of HCV in the development of Sjogren Syndrome (SS) is still unclear. HCV-RNA has been detected in whole salivary gland tissue, but there is no evidence that HCV infects salivary gland epithelial cells. However, epidemiologic and experimental data suggest that HCV may be involved in the pathogenesis of certain histotypes of B-cell non-Hodgkin's lymphoma, including those growing primarily in the salivary glands. The presence of HCV infection does not preclude the safe treatment of patients with hematologic malignancies using standard and high-dose chemotherapy. Salivary gland tumors are a diverse group of neoplasms, accounting for approximately 6 percent of neoplasms in the head and neck region.
What are the potential malignant oral disorders?5 answersOral potentially malignant disorders (OPMDs) are conditions that have an increased risk of developing into oral cancer. These disorders include oral leukoplakia, erythroplakia, oral submucous fibrosis (OSMF), proliferative verrucous leukoplakia, and other precancerous lesions.OPMDs are associated with a higher rate of occurrence of oral squamous cell carcinoma (OSCC), especially in regions where tobacco and arecanut consumption is prevalent, such as South Asian countries.The transformation of OPMDs into oral cancer is common, and early detection and timely treatment of these disorders can help prevent malignant progression.The immune checkpoint serves as a crucial regulator in the development of OPMDs and OSCC, and the expression of immune checkpoints like programmed death receptor-1 (PD-1) and programmed death receptor-1 ligand (PD-L1) has been observed in OPMDs.Early detection and prevention of OPMDs are essential to prevent their malignant transformation into oral cancer. Various diagnostic techniques are used to predict the progression and assess the risk of malignant transformation in OPMDs.
What factors contribute to the high incidence of oral cancer in Saudi Arabia?5 answersThe high incidence of oral cancer in Saudi Arabia can be attributed to several factors. One factor is the late presentation of patients, with a significant number of cases being diagnosed at advanced stages, leading to poor treatment outcomes and quality of life. Another factor is the low public literacy on oral cancer, with studies showing that both the general public and healthcare practitioners lack basic knowledge on risk factors, symptoms, and screening. Weak policies on oral cancer prevention and care strategies, such as the lack of restrictions on tobacco use and the absence of routine immunization against human papillomavirus, also contribute to the high incidence. Additionally, the changing lifestyle, adoption of a Western model, lack of cancer awareness, and social barriers towards cancer investigations are factors that may contribute to the increasing incidence of oral cancer in Saudi Arabia.