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Is hyaluronic acid an amino acid? 

Enzyme assay
Tissue engineering
Hyaluronic acid
Drug delivery
Hyaluronidase

Answers from top 9 papers

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Papers (9)Insight
Open access•Journal Article•DOI
Application of hyaluronic acid as carriers in drug delivery.
Gangliang Huang, Hualiang Huang 
14 Mar 2018-Drug Delivery
249 Citations
Hyaluronic acid has good biocompatibility, biodegradability, and nonimmunogenicity.
Book Chapter•DOI
Beneficial Effects of Hyaluronic Acid
P.N. Sudha, Maximas H. Rose 
01 Jan 2014-Advances in food and nutrition research
81 Citations
Hyaluronic acid paves the way for beneficial research and applications to the welfare of life forms.
Journal Article•DOI
Hyaluronic acid. A review of its pharmacology and use as a surgical aid in ophthalmology, and its therapeutic potential in joint disease and wound healing.
Karen L. Goa, Paul Benfield 
01 Mar 1994-Drugs
371 Citations
Tolerability profiles appear similar for various formulations of hyaluronic acid and in comparison with hydroxy
Journal Article•DOI
Self-consistent field theory investigation of the behavior of hyaluronic acid chains in aqueous salt solutions
E.A. Nogovitsin, Yu. A. Budkov 
15 Apr 2012-Physica A-statistical Mechanics and Its Applications
12 Citations
Hyaluronic acid is a high molecular weight linear polysaccharide, which has a multitude of roles in biological tissues.
Open access
Hyaluronic acid--a versatile biopolymer.
S W Tan, M R Johns, P F Greenfield 
01 Jan 1990
15 Citations
Hyaluronic acid is clearly a most valuable therapeutic biopolymer.
Journal Article•DOI
Conjugates of modified hyaluronic acid with amino compounds for biomedical applications.
Radovan Buffa, Lucie Odstrčilová, Petra Šedová, Ivana Basarabová, Jaroslav Novotný, Vladimír Velebný 
01 Jun 2018-Carbohydrate Polymers
14 Citations
Hyaluronic acid (HA) modified with an aldehyde group (HA-CHO) has enormous potential for the covalent attachment of the amino compounds and for the crosslinking of HA with bis or multi-functional amino linkers under physiological conditions.
Journal Article•DOI
Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion
Carole Schante, Guy Zuber, Corinne Herlin, Thierry F. Vandamme 
15 Aug 2011-Carbohydrate Polymers
17 Citations
Our results indicate that amidation of hyaluronic acid in an anhydrous solvent is effective and led to a degree of substitution of the carboxylic groups up to 100%.
Open access•Journal Article•DOI
Hyaluronidases of bacterial and animal origin.
Karl Meyer, Eleanor Chaffee, Gladys L. Hobby, Martin H. Dawson 
28 Feb 1941-Journal of Experimental Medicine
129 Citations
Since hyaluronic acid has also been found in the skin, this organ may play a considerable rôle in the metabolism of hyaluronic acid.
Open access•Journal Article•DOI
The effects of proteolytic enzymes on the hyaluronic acid complex of ox synovial fluid.
B. S. Blumberg, A. G. Ogston 
01 Jun 1957-Biochemical Journal
32 Citations
The results suggest the possibility that systems containing hyaluronic acid may be susceptible to proteinase action in vivo, and that such action may play a part in the pathology of diseases in which hyaluronic acid is affected.

Related Questions

Amino acids in asteroids4 answersAmino acids have been detected in asteroids and meteorites, suggesting their potential role in the origin of life on Earth. The Ryugu asteroid fragments from the Hayabusa2 mission contain amino acids, with N,N-dimethylglycine (DMG) being the most abundant in one particle. Another study found a wide diversity of amino acids in a highly primitive CM carbonaceous chondrite meteorite, indicating formation during aqueous alteration. Iron meteorites, which contain less carbon, were also found to have amino acids, suggesting that they should not be overlooked for contributions to early Earth. Additionally, amino acids have been detected in micrometeorites, further supporting the presence of these organic molecules in small solar system bodies. The high-pressure torsion method was used to simulate impacts by small solar system bodies on glycine, resulting in partial decomposition to ethanol, highlighting the possibility of the origin of ethanol detected in comets.
Does hyaluronic acid improve the healing of skin wounds?5 answersHyaluronic acid (HA) has been shown to improve the healing of skin wounds. Studies have demonstrated that the use of HA-based creams and gauze pads resulted in a reduction in wound surface area and an increase in re-epithelialization. HA is a natural polysaccharide with excellent biocompatibility and biodegradability, making it an appealing material for the synthesis of biomedical hydrogels for skin wound healing. Chemical modifications and crosslinking strategies have been developed to generate versatile HA-based hydrogels, which have promising applications in wound healing and tissue engineering. Additionally, the molecular weight of HA plays a role in its effects on wound healing, with high molecular weight HA serving an anti-inflammatory role and low molecular weight HA contributing to immunostimulation. Overall, the literature suggests that HA can improve the healing of skin wounds through various mechanisms, making it a promising biomaterial for clinical applications.
Is hyaluronic acid actually good moisturizer?5 answersHyaluronic acid is considered a good moisturizer based on the information provided in the abstracts. It has ideal moisturizing, nourishing, and lipid-clearing effects, making it suitable for current market demands. The hyaluronic acid moisturizing stoste, which contains hyaluronic acid as the main ingredient, has ideal effects of moisturizing, nourishing, and skin beautifying. The hyaluronic acid moisturizing hydrating mask, which also contains hyaluronic acid as the main raw material, effectively plays a hydration role, prevents moisture loss, and reduces the loss of hyaluronic acid in the skin, resulting in more moist, tender, and hydrated skin. A moisturizing hyaluronic acid composition, consisting of different molecular weight hyaluronic acids, provides an all-layer three-dimensional moisturizing effect on the skin and has an instant and long-lasting moisturizing effect. A moisturizing spray toner, containing cross-linked hyaluronic acid, sea silt extract, and hydrolyzed hyaluronic acid, is dedicated to replenishing water and moisturizing the skin.
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