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Is immunity a factor why people drinking water with e coli does not get sick? 

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Immunity can play a role in why some individuals drinking water contaminated with E. coli do not get sick. A study on an E. coli O157:H7 outbreak in Wyoming found that long-term exposure to contaminated water may lead to partial immunity, especially in adults. However, the presence of E. coli toxins in drinking water from improved sources can still pose a significant health risk, as these toxins were correlated with those found in stool samples of individuals with diarrhea who consumed the water. The study highlighted that contaminated drinking water can serve as a potential source of infection, emphasizing the importance of ensuring toxin-free water at the point of use to prevent illnesses associated with E. coli exposure.

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Partial immunity due to long-term exposure to contaminated water may explain why town residents had a lower attack rate of illness from E. coli O157:H7 compared to visitors in Alpine, Wyoming.
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Maternal immunity may confer protection against enteropathogenic E. coli, potentially reducing the likelihood of illness in individuals exposed to contaminated water.

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