Is it bad to inject stem cells?
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| It is also clear that there is a potential "dark side" to manipulating the stem cell compartment, as deregulation of somatic stem cells is being increasingly implicated in carcinogenesis and the generation of "cancer stem cells." | |
Open access•Journal Article 35 Citations | The age of infarction seems to be irrelevant to regenerative potency of stem cells, since stem cells therapy in old infarctions (many years old) is almost equally effective in comparison to previous infarcts. |
21 Citations | Oral stem cells have excellent potential for bone formation and can be successfully used to replace traditionally used bone marrow stem cells. |
23 Citations | It is likely, however that the major advance that stem cells have over more restricted cell types is their ability to modulate the responses of the immune system and to influence endogenous tissue stem cells to accentuate repair. |
14 Citations | These models indicate that the successful mobilization of stem cells into the peripheral blood is inversely proportional to exposure to stem cell toxic drugs. |
| Although stem cell-based therapy faces potential hurdles, it holds a potential hope to provide a safe, effective, and feasible clinical application of stem cells in AD patients. | |
112 Citations | Their use in the clinical setting, however, must be considered with caution because there is evidence that mesenchymal stem cells may also contribute to the maintenance of cancer stem cells. |
19 Citations | The use of embryonic stem cells or induced pluripotent stem cells in clinical settings is still limited due to cell regulation, genetic manipulation, and ethical considerations, even though these cells are highly beneficial. |
18 Citations | In fact, it is believed that this strategy may lower stem cell mortality and coerce aged stem cells into adopting more resilient phenotypes similar to that of their younger counterparts. |
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