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Is Leishmania donovani intracellular? 

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Visceral leishmaniasis
Cutaneous leishmaniasis
Leishmania
Leishmania infantum

Answers from top 4 papers

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Papers (4)Insight
Open access•Journal Article•DOI
Surface antigens of Leishmania donovani promastigotes.
D A Lepay, N Nogueira, Zanvil A. Cohn 
01 May 1983-Journal of Experimental Medicine
100 Citations
The possibility that this major surface antigen is shared, with minor differences, not only by L. donovani strains but between Leishmania species in general is suggested.
Journal Article•DOI
A proteomic approach to identify developmentally regulated proteins in Leishmania infantum.
Youssef El Fakhry, Marc Ouellette, Barbara Papadopoulou 
01 Aug 2002-Proteomics
111 Citations
These findings bring a new insight in our understanding of metabolic and energy requirements of the intracellular form of Leishmania.
Open access•Journal Article•DOI
Molecular and serological detection of Leishmania spp. in horses from an endemic area for canine visceral leishmaniasis in southeastern Brazil
Julia Cristina Benassi, Graziella Ulbricht Benvenga, Helena Lage Ferreira, Rodrigo Martins Soares, Diogo Tiago da Silva, Vanessa Figueredo Pereira, Vera Letticie de Azevedo Ruiz, Trícia Maria Ferreira de Sousa Oliveira 
01 Jun 2018-Pesquisa Veterinaria Brasileira
13 Citations
Results indicate the presence of Leishmania spp.
Journal Article•DOI
Schizodeme and zymodeme characterization of leishmania in the investigation of foci of visceral and cutaneous leishmaniasis
Ulisses Gazos Lopes, Hooman Momen, Gabriel Grimaldi, Mauro Célio de Almeida Marzochi, Raquel S. Pacheco, Carlos M. Morel 
01 Feb 1984-Journal of Parasitology
66 Citations
These results demonstrate the usefulness of an integrated biochemical approach in the identification of Leishmania.

Related Questions

Altered mitochondrial function in macrophage contribute to immunopathogenesis Visceral leishmaniasis. how?5 answersAltered mitochondrial function in macrophages plays a crucial role in the immunopathogenesis of Visceral leishmaniasis. Studies have shown that Leishmania parasites induce mitochondrial hyper-fission, depolarization, and oxidative stress in macrophages, leading to distinct immune outcomes. Additionally, Leishmania donovani promotes mitochondrial biogenesis in macrophages through the virulence glycolipid lipophosphoglycan, creating a metabolically adapted environment for parasite survival. This alteration in mitochondrial properties is associated with the establishment of a specialized intracellular niche favorable for Leishmania replication. The interplay between Leishmania-induced mitochondrial changes and the host immune response highlights the significance of mitochondrial function in shaping the immunopathogenesis of Visceral leishmaniasis.
What are intracellular virus ?4 answersIntracellular viruses are infectious units that rely on host cell machinery for their replication and survival. They infect living cells and replicate within them, using the cellular processes and resources to produce the components necessary for their own reproduction. Viruses are obligate intracellular parasites, meaning they can only multiply within cells and require internal membranous structures for various aspects of their life cycle. They do not possess their own protein synthesis machinery or energy-generating metabolic pathways, and instead re-route and modify cellular processes to optimize their reproduction. Understanding the interactions between viruses and the host cell cytoskeleton can provide insights into potential targets for drug therapies and vaccine development. Additionally, some viruses, such as vaccinia virus, have been shown to induce the formation of actin tails within host cells, similar to those used by pathogenic bacteria for cell-to-cell spread.
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