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RESULTS The included papers showed that Manuka honey can inhibit the process of carcinogenesis by controlling different molecular processes, and progression of cancer cells.
The action of manuka honey stems partly from a phytochemical component, so this type of honey might be more effective in vivo.
Our results indicated that Malaysian honey (specifically sourwood honey and longan honey) is a good source of antioxidants compared to Manuka honey.

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Euphorbia hirta is for treatment?
5 answers
Euphorbia hirta is utilized for the treatment of various ailments due to its medicinal properties. It has been traditionally used for conditions such as asthma, skin diseases, hypertension, jaundice, gonorrhea, and dengue. The plant exhibits pharmacological activities like anti-inflammatory, anti-biotic, anti-malarial, anti-bacterial, and anti-ulcer effects, similar to quinolone activity. Additionally, E. hirta has been found to possess antioxidant properties and is rich in bioactive compounds like polyphenols, flavonoids, steroids, tannins, and alkaloids, which contribute to its antimicrobial, anti-inflammatory, anti-diabetic, and anti-cancer activities. Research also suggests its potential in treating infectious diseases, respiratory infections, skin pathologies, and gastrointestinal disorders. Overall, Euphorbia hirta is a versatile herbal medicine with a wide range of therapeutic applications.
How does the concentration of kamias extract stain remover?
4 answers
The concentration of Kamias extract stain remover plays a crucial role in its effectiveness. Different concentrations of extracts, such as 100%, 75%, 50%, and 25%, have varying impacts on stain removal efficacy. Studies show that higher concentrations of extract tend to result in a more significant decrease in stain intensity and extension scores, requiring less frequent treatment for effective stain removal. Additionally, the synthesis of carbon nanodots from Kamias leaves for antibacterial wound dressings demonstrates that varying concentrations of C-nanodots exhibit antibacterial properties against specific bacteria, with different zones of inhibition at different concentrations. Therefore, the concentration of Kamias extract or its derivatives significantly influences the stain removal and antibacterial properties of the final product.
What the mechanism of antibacterial activity by probiotic?
4 answers
Probiotics exhibit antibacterial activity through various mechanisms. They compete for nutrients and adhesion sites, produce antimicrobial substances like bacteriocins, lactic acid, acetic acid, and hydrogen peroxide, and reduce intestinal pH. Additionally, probiotics strengthen the host immune system, inhibit biofilm formation, and combat drug resistance in pathogens. Genomic analysis helps identify genes responsible for antibacterial metabolite production, aiding in understanding the mechanisms of pathogen control by probiotics. Studies have shown that probiotic strains like Lactobacillus and Bifidobacterium display strong antipathogenic activities against oral pathogens, contributing to improved oral health. Overall, probiotics offer a multifaceted approach to combating antibiotic-resistant pathogens, making them a promising strategy for addressing challenging infections.
What concentrations of assafoetida used topical wound?
5 answers
Assafoetida, a resin from Ferula species, has shown potent antiparasitic effects on Trichomonas vaginalis, making it a promising candidate for treating parasitic infections. However, the specific concentrations of assafoetida used in topical wound healing were not explicitly mentioned in the provided contexts. On the other hand, silver sulfadiazine-based formulations, when combined with ingredients like camphor, menthol, and eucalyptus, have demonstrated significant improvements in wound healing rates, especially for burns and surgical wounds. Additionally, silver sulfadiazine creams formulated as sprays have been effective in promoting wound healing and reducing the risk of secondary infections, showcasing comparable antimicrobial activity to marketed formulations.
Which solvent is best to make essential oils solution for antimicrobial activities?
5 answers
The best solvent for making essential oil solutions for antimicrobial activities can vary based on the specific plant material and target microorganisms. Different solvents have been studied for their effectiveness in extracting antimicrobial compounds from plants. Polysorbate 80 (Tween 80) and dimethylsulfoxide (DMSO) have been investigated for their antibacterial activity. Additionally, natural deep eutectic solvents (NADES) have shown promising antimicrobial effects against various bacteria and fungi, including Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. Furthermore, the study on Kigelia africana highlighted that absolute ethanol, acetone, and ethanol 50% were effective solvents for extracting antimicrobial compounds from different plant parts. Therefore, depending on the specific plant material and target microorganisms, solvents like Tween 80, DMSO, NADES, and ethanol-based solvents can be considered for preparing essential oil solutions with antimicrobial properties.
Why is IONIZATION important for the action of sulphonamide antibacterial agents?
5 answers
Ionization plays a crucial role in the action of sulfonamide antibacterial agents due to its impact on the protonation preferences of these molecules. Research has shown that the protonation site of sulfonamide drugs in the gas phase differs from their solution-phase behavior, affecting their biological activity. Additionally, ionization radiation technology has been proposed as a method for effectively removing sulfonamide antibiotics from water without the need for pH adjustment or chemical agents, highlighting the significance of ionization in environmental applications of sulfonamides. Furthermore, the mechanism of action of sulfonamides involves competitive inhibition of folic acid synthesis, which is essential for microbial growth, emphasizing the importance of ionization in disrupting this process and exerting bacteriostatic effects.
Where is Stenochlaena palustris primarily found in Vietnam?
5 answers
Stenochlaena palustris, commonly known as climbing swamp fern, is primarily found in tropical and subtropical regions, including Vietnam. This fern species is utilized as an edible wild vegetable and in folk medicine by indigenous populations in Asia, showcasing its significance in the region. Phytochemical analyses have identified various compounds in S. palustris, such as kaempferol glycosides, fatty acids, and phytosterols, contributing to its diverse biological activities like antioxidant, antimicrobial, and termiticidal properties. Additionally, the fern's extracts have been shown to stimulate breast milk production in nursing mothers and find applications in food, cosmetics, and food packaging materials due to their antioxidant and antimicrobial potentials.
What are studies done on human cells with pathogens of plants?
4 answers
Studies have shown that human pathogens can contaminate plants, posing risks to public health. Recent research has highlighted the interactions between foodborne pathogens and plant surfaces, emphasizing the mechanisms of attachment, biofilm formation, and colonization by pathogens on plants. Additionally, investigations have revealed that human pathogens associated with plants often occur in low numbers but can still have significant consequences for public health and the economy. Collaboration between plant pathology and food safety communities has led to a better understanding of microbial contamination of food plants, particularly focusing on human enteric pathogens on plants (HPOPs). These studies underscore the importance of detecting and mitigating human pathogens on plants to ensure food safety and prevent foodborne illnesses.
Are there papers on the health benefits of moringa oleifera?
4 answers
Several research papers extensively discuss the health benefits of Moringa oleifera. Studies highlight its rich nutritional composition, including proteins, vitamins, minerals, and phytochemicals like flavonoids and isothiocyanates, which contribute to its anti-inflammatory, antioxidant, anti-carcinogenic, and other medicinal properties. Moringa is known for treating various ailments such as anaemia, asthma, pain, and diarrhoea due to its diverse pharmacological activities. Additionally, the plant's leaves are rich in essential phytochemicals and are used to combat malnutrition and enhance lactation, while its seeds are utilized in water treatment and as a natural coagulant. The comprehensive information provided in these papers underscores the potential of Moringa oleifera as a valuable medicinal plant with numerous health benefits.
What is the current situation in antibiotic resistance in bacteria?
5 answers
The current situation in antibiotic resistance in bacteria is a critical global health concern due to the overuse and misuse of antibiotics, leading to the emergence of multidrug-resistant bacteria. Antibiotic-resistant bacteria cause approximately 700,000 deaths annually, highlighting the urgent need for new antimicrobial therapies. The spread of resistance is facilitated by mobile genetic elements and resistant genes, affecting clinically important bacteria like MRSA, VRE, PRSP, and others. Strategies to combat antibiotic resistance include exploring alternative therapies like phagotherapy and drug repurposing, along with the development of new antibiotics through innovative approaches. The World Health Organization emphasizes the importance of immediate action to improve antibiotic use and accelerate research for new treatments to address the escalating threat of antibiotic resistance.
What are the current approaches to combating antibiotic resistance in bacteria?
5 answers
Current approaches to combating antibiotic resistance in bacteria include utilizing nanotechnology, developing antimicrobial materials and drug delivery systems, exploring novel therapeutic methods like phage therapies, immunotherapeutics, and nanoantibiotics, discovering new antibiotics, improving existing antibiotics, and pursuing alternatives such as bacteriophages, anti-biofilm drugs, probiotics, nanomaterials, vaccines, and antibody therapies. Additionally, combinational antibiotic therapy has been highlighted as an effective strategy to overcome antimicrobial resistance mechanisms. These diverse strategies aim to address the growing threat of antibiotic resistance by enhancing the efficacy of current treatments, developing new therapeutic options, and preventing the inappropriate use of antibiotics, ultimately contributing to the preservation of our antibiotic arsenal and public health.