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This may be an effective treatment for refractory epilepsy.
Therefore, metabolic treatments appear to be promising alternative approaches for epilepsy.

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What are the effects of Vitamin D deficiency on epilepsy?5 answersVitamin D deficiency has been found to have negative effects on epilepsy. Studies have shown that the intake of antiepileptic drugs (AEDs) can lead to vitamin D deficiency in both children and adults, with prevalence rates reaching 40% or higher. This deficiency can result in impaired bone mineralization and increased risk of osteomalacia and osteoporosis. Risk factors for vitamin D deficiency in patients with epilepsy include obesity and the use of enzyme-inducing AEDs. It is important to introduce laboratory screening for vitamin D deficiency among pediatric and adult patients with epilepsy and consider the inclusion of vitamin D in the treatment protocols for epilepsy to address these issues. Severe hypocalcemia due to vitamin D deficiency can also lead to convulsions, emphasizing the importance of vitamin D supplementation.
What is the role of Vitamin D in epilepsy?4 answersVitamin D has been studied for its potential role in epilepsy. It has been found to have neuroprotective, immunomodulatory, and brain development effects, which may be beneficial in the treatment of epilepsy. Studies have shown that vitamin D levels are often deficient or insufficient in patients with epilepsy. Vitamin D supplementation has been found to increase the antiepileptic effects of certain medications in animal models. In a pilot study, high-dose oral vitamin D3 was well tolerated and resulted in increased vitamin D levels in subjects with drug-resistant epilepsy. However, more research is needed to fully understand the role of vitamin D in epilepsy and its potential as a treatment option.
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