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These observations increase our understanding of the mechanisms of RNA virus evolution.
The interface between the transcripts of RNA viruses and the various RNA regulatory processes in the cell, therefore, has high potential to significantly impact virus gene expression, regulation, cytopathology and pathogenesis.
These findings may lead to a mechanistic understanding of RNA virus error catastrophe and improved anti-viral strategies.
These data suggest that RNA virus mutagens may represent a promising new class of antiviral drugs.
Additionally, RNA silencing in response to one virus may cross-protect against infection by another closely related virus.
The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus transmission.
The results also highlight the possibility of utilizing the small RNA in inhibiting at least three serotypes of the virus.
The results show that an RNA plant virus such as RYMV evolves as rapidly as most RNA animal viruses.
Furthermore, understanding RNA biology from the perspective of an RNA virus can shed considerable light on the broad impact of these post‐transcriptional processes in cell biology.
It appears unlikely, therefore, that RNA is a constituent of either virus.