scispace - formally typeset
Search or ask a question

Is stripping the membranes the same as losing your mucus plug? 

Mucociliary clearance
Mucin
Cystic fibrosis
Mucus
Low protein

Answers from top 10 papers

More filters
Papers (10)Insight
Journal Article•DOI
A computational study of mucociliary transport in healthy and diseased environments
Hanliang Guo, Eva Kanso 
03 Jul 2017-European Journal of Computational Mechanics
15 Citations
In contrast, when the periciliary layer is depleted, mucus hinders transport and stiffer mucus leads to a substantial decrease in transport efficiency.
Open access•Journal Article•DOI
Unplugging Mucus in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Marcus A. Mall
26 Apr 2016-Annals of the American Thoracic Society
43 Citations
Collectively, these studies demonstrate that airway surface dehydration is sufficient to produce mucus obstruction even in the absence of mucus hypersecretion and support further clinical testing of hydrating agents as a promising therapeutic strategy to unplug mucus in CF and COPD.
Open access•Journal Article•DOI
The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH.
Ying Ying Wang, Samuel K. Lai, Samuel K. Lai, Laura M. Ensign, Laura M. Ensign, Weixi Zhong, Richard A. Cone, Justin Hanes, Justin Hanes 
09 Dec 2013-Biomacromolecules
58 Citations
Our work also suggests additional components in mucus secretions, typically eliminated during mucin purification and reconstitution, may play an important role in maintaining the protective properties of mucus.
Journal Article•DOI
Mucosal prelamination of a radial forearm flap for intraoral reconstruction
Thomas Rath, Werner Millesi, Gabriele Millesi-Schobel, Susanna Lang 
01 Oct 1997-Journal of Reconstructive Microsurgery
23 Citations
A disadvantage is that mucus production will be absent, because mucosal and lining reconstruction is performed with tissue lacking mucus-providing qualities.
Open access•Journal Article•DOI
Therapeutic options for hydrating airway mucus in cystic fibrosis.
Bernadett Tildy, Duncan F. Rogers 
01 Jan 2015-Pharmacology
29 Citations
Summary: Rehydrating mucus increases MCC.
Open access•Journal Article•DOI
Probing the potential of mucus permeability to signify preterm birth risk.
K. B. Smith-Dupont, Caroline E. Wagner, Jacob Witten, K. Conroy, H. Rudoltz, Kelly Pagidas, Kelly Pagidas, V. Snegovskikh, Michael House, Katharina Ribbeck 
04 Sep 2017-Scientific Reports
27 Citations
Thus, although both microstructural rearrangements of the components of mucus as well as biochemical modifications to their adhesiveness may alter the overall permeability of the cervical mucus plug, our findings suggest that the latter mechanism plays a dominant role in the impairment of the function of this barrier during preterm birth.
Journal Article•DOI
Mucus as a Barrier to Drug Delivery – Understanding and Mimicking the Barrier Properties
Marie Boegh, Hanne Mørck Nielsen 
01 Mar 2015-Basic & Clinical Pharmacology & Toxicology
240 Citations
Consequently, mucus forms a steric barrier, and due to its negative charge and hydrophobic domains, the overall hydrophilic mucus also presents an interactive barrier limiting the free diffusion of components within and through the mucus.
Journal Article•DOI
Mucus can change the permeation rank order of drug candidates.
Ellen Hagesaether, Elisabeth Christiansen, Maria E Due-Hansen, Trond Ulven 
16 Aug 2013-International Journal of Pharmaceutics
8 Citations
These results indicate that an experimental system without mucus can give a faulty rank order of permeation compared to mucous membranes when structurally related drug candidates are tested.
Journal Article•DOI
pH- and protein-dependent buffer capacity and viscosity of respiratory mucus. Their interrelationships and influence of health
Bo Holma, Per Olof Hegg 
01 Aug 1989-Science of The Total Environment
72 Citations
Alternatively, persons with higher concentrations of mucus proteins will risk effects caused by increased mucus viscosity.
Journal Article•DOI
Transport properties and aggregation phenomena of polyoxyethylene sorbitane monooleate (polysorbate 80) in pig gastrointestinal mucin and mucus
Géraldine Lafitte, Krister Thuresson, P. Jarwoll, Magnus Nydén 
26 Sep 2007-Langmuir
26 Citations
On the other hand, the transport is slowed down in mucus due to interactions with other components such as lipids depots.

Related Questions

Can you do membrane sweep with mucus plug?10 answers
Can you get your membranes stripped if you lost your mucus plug?7 answers
Can you have a membrane sweep if you haven't lost your mucus plug?8 answers
Can you strip your own membranes during pregnancy?10 answers
Does stripping membranes remove mucus plug?10 answers
When is the earliest a doctor will strip your membranes?9 answers

See what other people are reading

What is the major finding in Comprehensive molecular portraits of human breast tumours?
5 answers
What is the major finding in Comprehensive molecular portraits of human breast tumours?
5 answers
How do Bifidobacterium Lactis B420 and Pasteurized Akkermansia Muciniphila interact in the microbiome?
5 answers
Bifidobacterium lactis B420 and pasteurized Akkermansia muciniphila interact in the microbiome by potentially modulating gut health and immune responses. B. lactis B420 is known for its beneficial effects on the host, while pasteurized A. muciniphila has shown promising results in improving health status, gut integrity, and immune response. Both probiotics have been linked to enhancing intestinal barrier function and reducing inflammation. Additionally, A. muciniphila has been associated with positive health outcomes, such as improving type II diabetes and obesity, and its beneficial effects are further enhanced after pasteurization. These interactions may contribute to a balanced gut microbiome, promoting overall health and potentially preventing diseases in the host.What are the common causes of human milk insufficiency?
5 answers
Human milk insufficiency can stem from various factors. One significant cause is the inadequacy of milk synthesis due to epigenetic modifications like RNA methylation, which affect gene expression and milk production. Additionally, lactation insufficiency can result from low protein levels in breast milk, leading to malnutrition in preterm infants despite fortified feeding. Cultural and lifestyle changes, such as transitioning from a seminomadic to a sedentary lifestyle, can also contribute to perceived milk insufficiency, prompting mothers to introduce bottle feeding for rest, regardless of actual milk production levels. Furthermore, the lack of constant contact between mother and infant may play a role in milk insufficiency, as emphasized in contrasting views on the importance of maternal-infant interaction for successful breastfeeding.Why ruminants raisers in rural areas did not use ummb for ruminants raised?
5 answers
Ruminant raisers in rural areas may not extensively use Urea Molasses Multinutrient Blocks (UMMB) due to various reasons. The fibrous feeds commonly available in rural settings are deficient in essential nutrients like protein, energy, and minerals, necessitating additional supplements for animal maintenance and productivity. Additionally, the utilization of agricultural waste as animal feed faces challenges due to its low quality, high fiber content, and low digestibility, requiring the addition of high-quality feed ingredients. Despite the potential benefits of UMMB in improving feed efficiency, digestibility, and animal productivity, the adoption rate might be hindered by the complexity of the technology involved in UMMB production and the labor-intensive nature of urea treatment methods for improving feed quality.Why does pseudomonas produce red currant jelly sputum?
5 answers
Pseudomonas aeruginosa can produce a characteristic red currant jelly sputum due to its physiology and interactions in the cystic fibrosis (CF) lung environment. The sputum layer in CF provides P. aeruginosa with nutrients for high-density growth. Different artificial sputum media formulations can lead to varied phenotypes and chemotypes in P. aeruginosa, influenced by components like mucin containing high iron levels. Evolutionary diversification in P. aeruginosa populations within artificial sputum medium biofilms can result in phenotypic variants, including loss of motility and antibiotic resistance. Visualizing P. aeruginosa within CF sputum using tissue clearing techniques reveals spatial organization characteristics like biofilm formation and exopolysaccharide production. Overall, the complex nutritional composition of the CF sputum environment and the interactions of P. aeruginosa within it contribute to the production of red currant jelly sputum.What is the role of neutrophils in cystic fibrosis lung infections?
5 answers
Neutrophils play a crucial role in cystic fibrosis (CF) lung infections. In CF, the loss of function of the Cystic Fibrosis Transmembrane-conductance Regulator (CFTR) gene leads to aberrant neutrophil behavior, including premature priming and dysregulated responses to challenges. Neutrophils in CF lungs are defective in producing hypochlorous acid, providing a survival advantage to specific pathogens like Pseudomonas aeruginosa and Staphylococcus aureus. Moreover, in CF airways, a subset of neutrophils releases tissue-damaging neutrophil elastase, contributing to lung damage. Studies show that neutrophils efficiently kill Mycobacterium avium when opsonized with plasma factors from healthy donors, highlighting the importance of complement opsonization in neutrophil-mediated killing of pathogens in CF.What valuable molecules slaughterhouse side stream bovine trachea has?
4 answers
The bovine trachea, a slaughterhouse side stream, contains valuable molecules such as collagen, tracheal antimicrobial peptide (TAP), and link protein. Collagen, abundant in the trachea, is a structural protein found in various animal organs. TAP, with microbicidal activity, is induced by Pam3CSK4, IL-17A, and lipopolysaccharide, enhancing innate immunity in cattle. Additionally, the link protein from bovine trachea binds divalent cations and is only soluble in low ionic strength solutions, indicating its unique properties and potential applications. These molecules highlight the diverse and beneficial components present in the bovine trachea, showcasing its potential for various industrial and biomedical uses.Why is gelatin not a significant source of protein?
5 answers
Gelatin is not considered a significant source of protein due to various reasons highlighted in the research papers. Studies show that gelatin, derived from collagen, lacks all indispensable amino acids, impacting its protein quality and bioavailability in low protein diets. Additionally, gelatin's effects on bone mineral density and body weight differ from those of other protein sources like casein, indicating its limitations in providing essential nutrients. Furthermore, gelatin extracted from marine sources, such as jellyfish, has been found to have inferior gel properties compared to fish and bovine gelatins, attributed to the absence of key collagen proteins necessary for gel network formation. Despite being a rich source of animal protein, gelatin's nutritional value is compromised by its amino acid profile and lack of essential nutrients, making it less significant as a protein source in dietary applications.What is the relation between dietary protein intake and hand grip strength of womens?
5 answers
Dietary protein intake plays a crucial role in hand grip strength (HGS) among women. Research indicates that women with low grip strength tend to have significantly lower total and animal protein intake compared to those with normal grip strength. Additionally, consuming protein above the estimated average requirement (EAR) and incorporating protein from legumes into the diet can reduce the likelihood of low grip strength in elderly women. Furthermore, higher protein intake is associated with greater appendicular lean mass adjusted for BMI (ALMBMI) and hand grip strength adjusted for BMI (GSMAXBMI) in middle-aged women, emphasizing the positive impact of protein on muscle mass and strength in this demographic. Therefore, ensuring adequate protein intake, especially from diverse sources, is essential for maintaining hand grip strength and overall muscle health in women across different age groups.What are the potential effects of high protein intake on urea production and excretion in humans?
5 answers
High protein intake can lead to increased urea production and excretion in humans, impacting health and the environment. Excessive protein consumption beyond physiological needs results in the degradation of excess amino acids, leading to elevated nitrogen excretion in the form of urea. In critically ill patients, high protein administration can increase ureagenesis, potentially causing harm and inefficacy. However, in the general population, high protein intake is associated with elevated cardiovascular event risks, with both low and high protein intake levels showing higher event rates compared to moderate intake. Contrarily, a study on pre-diabetic individuals found that increased protein intake did not impair kidney function after one year, although it did lead to higher urea excretion levels. These findings highlight the complex interplay between protein intake, urea production, and health outcomes in diverse populations.