Is the malaria vaccine RNA?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
22 May 2017 47 Citations | These data justify progression of this next generation AMA1 vaccine towards human trials. Malaria: Inhibiting parasite invasion of red blood cellsA vaccine targeting a protein complex that allows malaria-causing parasite to enter red blood cells has been produced. |
| RNA, on the other hand, is readily taken up and expressed by DC, making it an alternative vaccine candidate. | |
Open access•Journal Article 21 Citations | Although much progress is required for the development of a vaccine that provides sustainable protective immunity against malaria, a strategy using DNA vaccine technology as a core component of such a vaccine is promising. |
68 Citations | Currently, there is no licensed vaccine against malaria, but an efficacious vaccine would represent an important public health tool for successful malaria elimination. |
| DNA-based vaccines are a new technology that may hold hope for an effective malaria vaccine. | |
15 Citations | Hybrid molecules of this type may be the basis of a malaria vaccine. |
479 Citations | Our findings demonstrate that a safe and effective, genetically attenuated whole-organism malaria vaccine is possible. |
17 Citations | Two human models of immunity to malaria, however, suggest that the development of an effective vaccine is within reach. |
58 Citations | With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently needed intervention. |
23 Citations | We therefore developed a semi-synthetic whole parasite malaria vaccine that is easily manufactured and stored. |