Research on insulin as a life saving drug
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| Papers (8) | Insight |
|---|---|
7 Citations | The discovery of insulin saved the life of the diabetic. |
| Significance The discovery and characterization of insulin, a key hormone of energy metabolism, provided a life-saving drug for diabetics. | |
10 Citations | The history of insulin discovery here reported is fascinating; insulin is a hormone, a product of biotechnology, a field of research that saved and save the life of many diabetic patients. |
| A range of research articles on current trends and recent advances in insulin has been summarized, which led us to the conclusion that multiple daily insulin injections or continuous subcutaneous insulin infusion (insulin pump) is the best method to manage diabetes mellitus. | |
7 Citations | Acutely, insulin may be a life-saving drug with immediate dramatic effects. |
15 Citations | This validates the use of the bloodspot insulin assay as a potential research tool for large-scale epidemiological studies. |
70 Citations | If there is adequate incentive to continue a broad-based research effort into novel approaches to insulin delivery, the quality of life of persons with diabetes can be improved in the not too distant future. |
09 Oct 2015 | insulin is a valuable drug for, those who are in need of it. |
Related Questions
Does insulin play a role in brain function and cognition?5 answersInsulin plays a role in brain function and cognition. Recent studies suggest that insulin signaling in the brain may modify cognitive ability through unknown pathways. Insulin resistance, which is reduced sensitivity to the action of insulin, has been associated with cognitive impairment and neurodegeneration. Brain insulin signaling is important for weight regulation, mental health, and healthy cognition. Brain insulin levels are linked to memory, learning, and neurodegenerative diseases like Alzheimer's disease. Neuroimaging studies have shown that insulin resistance is related to cerebral abnormalities in brain regions associated with cognitive processes, such as the medial temporal lobe and prefrontal lobe. Overall, insulin plays a multifactorial role in the brain, including neuronal and glial metabolism, glucose regulation, and cognitive processes.
Why is insulin the recommended drug for type 1 diabetes?5 answersInsulin is the recommended drug for type 1 diabetes because it mimics the physiological insulin secretion that occurs in individuals without diabetes. Intensive insulin therapy, whether by multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII), is the fundamental therapy for type 1 diabetes at all ages. Insulin analogues offer advantages over human insulin in type 1 diabetes treatment. Insulin therapy aims to achieve glycemic control goals established for the age group, and periodic reassessment of insulin doses is necessary to avoid clinical inertia in treatment. Insulin is also the primary treatment for type 1 diabetes mellitus (T1DM). It is typically initiated with multiple daily injections of short-acting or rapid-acting insulin analogues, together with one or more daily separate injections of intermediate or long-acting insulin. Insulin therapy is essential in patients with T1DM to minimize hyperglycemia, severe hypoglycemia, hypoglycemic unawareness, and the development of long-term complications.
How does exercise effect the action of insulin?5 answersExercise has a significant impact on the action of insulin. During physical activity, insulin secretion is inhibited, and fuel mobilizing processes are activated to suppress the fuel storage effects of insulin. Exercise-related changes in insulin action and glucose homeostasis occur primarily in the skeletal muscle, where glucose uptake happens through insulin-independent mechanisms that converge with insulin-signaling pathways. Exercise also improves insulin responses by recruiting muscle microvasculature to increase insulin delivery and action in the muscle. Different types of exercise, such as endurance exercise and resistance training, can increase insulin sensitivity and stimulate glucose transporter type 4 (GLUT-4) translocation to the cell surface. However, a ten-week exercise training program may not have a significant effect on insulin action in healthy sedentary postmenopausal women.
What are the effects of insulin on blood sugar levels?4 answersInsulin has various effects on blood sugar levels. It rapidly lowers blood glucose levels by inhibiting endogenous glucose production and stimulating glucose uptake. Insulin also has direct effects on the liver, leading to the rapid inhibition of glycogenolysis, and indirect effects mediated via peripheral actions, mostly modulating lipolysis. In addition, insulin exerts long-term effects on liver gene expression and function, which can significantly affect the acute responses to an increase in circulating insulin levels. Insulin injection in normothermic rats causes a significant fall in blood sugar levels, but it tends to rise again within a few hours. However, in hypothermic rats, insulin injection leads to a significant and prolonged decrease in blood sugar levels, with little tendency for it to rise again. Overall, insulin plays a crucial role in regulating blood sugar levels through its direct and indirect effects on glucose production and uptake.
What is the definition of a life-saving boat?5 answersA life-saving boat is a type of boat designed to rescue people in emergency situations, particularly in water-related incidents. These boats are equipped with various features and mechanisms to ensure the safety of both rescuers and those being rescued. The life-saving boat chairis a simple and convenient chair that can be transformed into an escape chair in dangerous conditions. The life-saving floating boatis capable of remotely dispatching rescue and has propeller devices for propulsion. The life-saving boat launching devicehas a support frame with a glide and a propulsion force generation unit using compressed air. The remote control boat with an expansible auxiliary tubeis controlled remotely and has an auxiliary tube that expands to save drowning persons. The life-saving unmanned boat carrying a turnover type life saving devicehas a rotating bracket and a pocket basket for effective water rescue.
What is the use of insulin treatment for diabetes?5 answersInsulin treatment is essential for the management of both type 1 and type 2 diabetes. It is a key player in controlling hyperglycemia in patients with type 1 diabetes and selected patients with type 2 diabetes. Before the discovery of insulin in 1922, patients with type 1 diabetes were placed on a starvation diet and survival was limited. Insulin therapy is life-saving for people with type 1 diabetes and is also needed in a significant number of people with type 2 diabetes to optimize glycemic control. The traditional method of insulin administration is through subcutaneous injection, but there have been advancements in insulin delivery systems, including insulin syringes, infusion pumps, jet injectors, and pens. Non-invasive delivery of insulin has been a major goal, and emerging technologies such as insulin inhalers, insulin buccal spray, insulin pill, islet cell transplant, and stem cell therapy are being explored as treatment options. Insulin initiation in type 2 diabetes requires careful consideration and strategies to overcome barriers. Good glycemic control in type 2 diabetes can be achieved through the use of insulin.