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What affects tumor angiogenesis? 

Cancer
Neovascularization
Tumor progression
Angiogenesis
Angiogenic Switch

Answers from top 10 papers

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Papers (10)Insight
Journal Article•DOI
Breast cancer increases initiation of angiogenesis without accelerating neovessel growth rate
James C. Watson, James G Redmann, Michael O. Meyers, Robert C Alperin-Lea, Bryan M. Gebhardt, Joseph B. Delcarpio, Eugene A. Woltering 
01 Aug 1997-Surgery
26 Citations
Tumor enhancement of angiogenesis may occur by increased initiation of the angiogenic response.
Journal Article•DOI
Common responses of tumors and wounds to hypoxia.
Valéry Payen, Lucie Brisson, Mark W. Dewhirst, Pierre Sonveaux 
01 Mar 2015-Cancer Journal
43 Citations
These effects in tumor account for further molecular and metabolic changes and for a persistent stimulation of angiogenesis.
Open access•Journal Article•DOI
Antiangiogenic Resistance: Novel Angiogenesis Axes Uncovered by Antiangiogenic Therapies Research.
Gabriela Jiménez-Valerio, Oriol Casanovas 
30 Nov 2016-Current Drug Targets
10 Citations
Hence, inhibiting angiogenesis affects tumor growth and proliferation in patients with different types of cancer.
Open access•Journal Article•DOI
Pathophysiology of tumor neovascularization.
Mitsuko Furuya, Mariko Nishiyama, Yoshitoshi Kasuya, Sadao Kimura, Hiroshi Ishikura 
01 Jan 2005-Vascular Health and Risk Management
63 Citations
In cancer therapy, for example, modulation of factors responsible for tumor angiogenesis may be beneficial in inhibiting of tumor progression.
Open access•Journal Article
Role of angiogenesis in drug resistance.
Jürgen Mattern
01 Nov 2001-Anticancer Research
10 Citations
Therefore, the extent of tumor angiogenesis may well be an important factor contributing to the difficulty of successful therapy in certain tumor types.
Open access•Journal Article•DOI
A novel four-step system for screening angiogenesis inhibitors.
Qin Zhou, Cuiling Qi, Yan Li, Xiaodong He, Jiangchao Li, Qianqian Zhang, Lan Tian, Ming Zhang, Zhe Han, Huiping Wang, Xuesong Yang, Lijing Wang 
01 Dec 2013-Molecular Medicine Reports
9 Citations
Angiogenesis exhibits a significant effect on tumor progression.
Journal Article•DOI
Venous thromboembolism in patients with cancer and its relationship to the coagulation cascade and vascular endothelial growth factor.
Mutlu Dogan, Ahmet Demirkazik 
01 Oct 2005-Supportive Cancer Therapy
18 Citations
Therefore, angiogenesis facilitates tumor growth, invasion, and metastasis.
Journal Article•DOI
Endothelial‐like cells derived directly from human tumor xenografts
Gangadharan B. Sajithlal, Terence F. McGuire, Jie Lu, Donna Beer-Stolz, Edward V. Prochownik, Edward V. Prochownik 
15 Nov 2010-International Journal of Cancer
15 Citations
These findings could have significant implications for therapies that target tumor angiogenesis.
Journal Article•DOI
Anti-angiogenesis in cancer therapy.
Paula M. Muehlbauer
01 Aug 2003-Seminars in Oncology Nursing
22 Citations
Tumor angiogenesis is a complex, multistep process that provides a target for antineoplastic therapy whereby tumor neovasculature is interrupted at various steps in the angiogenic process.
Open access•Journal Article•DOI
Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism.
Chengjian Zhao, Wei Zhang, Yu-Wei Zhao, Yun Yang, Hui Luo, Gaili Ji, E. Dong, Hongxing Deng, Shuo Lin, Shuo Lin, Yuquan Wei, Hanshuo Yang 
14 Jan 2016-Scientific Reports
13 Citations
These findings establish that tumor angiogenesis play a much earlier and broader role in promoting tumor growth, which is independent of vascular circulation.

Related Questions

What is the process of angiogenesis?5 answersAngiogenesis is the process by which new blood vessels are formed from preexisting vessels. It can occur naturally during organ growth and development or can be induced by a cancerous tumor. Angiogenesis involves the sprouting of new blood capillaries from existing vessels. This can be achieved through endothelial sprouting or nonsprouting microvascular growth, known as intussusceptive microvascular growth (IMG). The formation of new blood and lymphatic vessels is essential for tumor growth and metastasis, as it allows tumor cells to acquire nutrients and oxygen and remove waste products. Understanding the process of angiogenesis is crucial for studying cancer biology and developing anti-cancer treatments.
How does angiogenesis help tumour growth?5 answersAngiogenesis, the formation of new blood vessels, plays a crucial role in tumor growth. Tumors require a sufficient supply of nutrients and oxygen, which is facilitated by the development of new blood vessels. The induction of angiogenesis allows tumor cells to grow, invade, and metastasize. Pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), promote the remodeling of the extracellular matrix and changes in perivascular cell structure, as well as endothelial cell changes and migration. These factors tip the balance in favor of pro-angiogenic factors, leading to increased tumor progression and a state where proliferation is favored over apoptosis. Angiogenesis is a complex process regulated by various cytokines and chemokines present in the tumor microenvironment. Understanding the metabolic mechanisms driving the differences between normal and tumor vasculature is crucial for developing targeted therapies against tumor angiogenesis.
What are angiogenic motifs?3 answersAngiogenic motifs are sequences within proteins that play a role in the process of angiogenesis, which is the formation of new blood vessels from existing ones. These motifs can be found in various angiogenic factors and are involved in initiating specific events within the complex cascade of pathways that lead to angiogenesis. However, the exact nature and characteristics of angiogenic motifs are still being studied.
Can tumors manipulate angiogenesis?9 answers
Do oncogenes affect tumor angiogenesis?10 answers
Which vitamin has the most powerful anti angiogenic properties?10 answers

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