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Previous studies have shown that a mixture of amino acids, consisting of 9 essential amino acids and 3 non-essential amino acids was effective in facilitating muscle recovery from athletic activities.
Since it is known that amino acid supplementation stimulates the transport of amino acids into the skeletal muscles, and administration of exogenous amino acids after exercise increases protein synthesis while reducing protein breakdown, it is plausible that amino acid supplementation is effective for reducing muscle damage and / or enhancing recovery from muscle damage.
We conclude that amino acids like arginine and lysine may hasten fracture healing.
These findings suggest that dietary amino acids can directly affect molecular signaling in skeletal muscle, further indicating that dietary manipulation with specific amino acids could potentially attenuate muscle loss with dietary protein deficiency.
Key pointsTaurine ingestion significantly decreased certain amino acids in skeletal muscles accompanied with enhanced exercise performance. The decreased amino acids in common were threonine, serine, and glycine, but not alanine; pyruvate precursor for gluconeogenesis. The alteration of three amino acids in muscles was maintained after exhausted exercise. The muscular alterations of them might be one of taurine-induced roles on exercise performance.
The results obtained in the study suggest that in trauma patients high ratios of essential amino acids/total nitrogen are needed and that amino acid solutions enriched in branched chain amino acids are most effective in preventing muscle catabolism and promoting protein synthesis.
Open accessJournal ArticleDOI
01 Apr 1986-Annals of Surgery
65 Citations
Reduced uptake of amino acids by skeletal muscle during sepsis may divert amino acids to the liver for increased gluconeogenesis and protein synthesis.
An excess of branched-chain amino acids in the presence of an optimal profile of other essential amino acids acutely increased muscle protein synthesis and glutamine flux from skeletal muscle in cancer patients after surgery.
52, 2323 (1988)], indicating that aminopeptidase C and hydrolase H are responsible for the increment of free amino acids during aging of these muscles.
Exercise and exogenous amino acids have an additive effect on muscle protein synthesis.

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